Potential complications of CAD/CAM-produced resin composite crowns on molars: A retrospective cohort study over four years

Miyu Inomata, Akio Harada, Shin Kasahara, Taro Kusama, Akane Ozaki, Yusuke Katsuda, Hiroshi Egusa

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)


Purpose Evaluation of the clinical performance of computer-aided design/computer-aided manufacturing-produced resin composite crowns (CAD/CAM composite crowns) on molars with a particular focus on placement location. Methods A retrospective cohort study was performed based on the clinical records of patients with CAD/CAM composite crowns on molars (June 2016 to March 2021). The hazard ratios (HRs) and 95% confidence intervals (95% CIs) were estimated based the Cox proportional hazard model to evaluate the effect of tooth location on complication type and occurrence. Covariates included crown location (maxilla/mandible, distalmost tooth/not distalmost tooth, and first molar/second or third molar) and endodontically treated (nonvital) or untreated (vital) tooth. Results Overall, 362 crowns were evaluated (mean follow-up: 378 days, median: 286 days), and 106 crowns (29.3%) showed complications, most frequently crown debonding. The cumulative success and survival rates were 70.9% and 93.7%, respectively, after 1 year and 49.5% and 86.5%, respectively, after 3 years. There was no significant difference in the HRs and log-rank tests in the Kaplan–Meier curves based on crown location parameters (P > 0.05). However, placement on vital teeth was associated with higher risks than on nonvital teeth (HR, 1.55; 95% CI, 1.03–2.23). In addition, the cement as a covariate yielded a high HR. Conclusions The location of CAD/CAM composite molar crowns is unlikely a risk factor for complications; therefore, these crowns can be clinically applied to all molars. However, the application of such molar crowns to vital teeth and the use of a cement other than adhesive resin cement present risks.

Original languageEnglish
Article numbere0266358
JournalPloS one
Issue number4 April
Publication statusPublished - 2022 Apr

ASJC Scopus subject areas

  • General


Dive into the research topics of 'Potential complications of CAD/CAM-produced resin composite crowns on molars: A retrospective cohort study over four years'. Together they form a unique fingerprint.

Cite this