TY - JOUR
T1 - Practical Methods for Chemical Inactivation of Creutzfeldt-Jakob Disease Pathogen
AU - Tateishi, Jun
AU - Tashima, Takatoshi
AU - Kitamoto, Tetsuyuki
N1 - Copyright:
Copyright 2017 Elsevier B.V., All rights reserved.
PY - 1991
Y1 - 1991
N2 - Chemical inactivation of pathogen of Creutzfeldt-Jakob disease (CJD) was examined using the mouse-adapted CJD strain. A high concentration of formic acid, guanidine compounds, trichloroacetate and phenol prevented CJD transmission. NaOH between 0.25 and 2 n lengthened the incubation periods. Sodium dodecyl sulfate (SDS) in a concentration between 1 and 3% did not alter incubation at room temperature but did completely block the transmission after boiling for 3 min in 3% SDS. This method is recommended for practical disinfection.
AB - Chemical inactivation of pathogen of Creutzfeldt-Jakob disease (CJD) was examined using the mouse-adapted CJD strain. A high concentration of formic acid, guanidine compounds, trichloroacetate and phenol prevented CJD transmission. NaOH between 0.25 and 2 n lengthened the incubation periods. Sodium dodecyl sulfate (SDS) in a concentration between 1 and 3% did not alter incubation at room temperature but did completely block the transmission after boiling for 3 min in 3% SDS. This method is recommended for practical disinfection.
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U2 - 10.1111/j.1348-0421.1991.tb01544.x
DO - 10.1111/j.1348-0421.1991.tb01544.x
M3 - Article
C2 - 1909414
AN - SCOPUS:0025975320
SN - 0385-5600
VL - 35
SP - 163
EP - 166
JO - Microbiology and Immunology
JF - Microbiology and Immunology
IS - 2
ER -