Prenatal antibiotic use, caesarean delivery and offspring's food protein-induced enterocolitis syndrome: A National Birth Cohort (JECS)

TY - JOUR

T1 - Prenatal antibiotic use, caesarean delivery and offspring's food protein-induced enterocolitis syndrome

T2 - A National Birth Cohort (JECS)

AU - for the Japan Environment and Children's Study (JECS) Group

AU - Yamamoto-Hanada, Kiwako

AU - Pak, Kyongsun

AU - Saito-Abe, Mayako

AU - Sato, Miori

AU - Miyaji, Yumiko

AU - Mezawa, Hidetoshi

AU - Nishizato, Minaho

AU - Yang, Limin

AU - Kumasaka, Natushiko

AU - Nomura, Ichiro

AU - Ohya, Yukihiro

AU - Kamijima, Michihiro

AU - Yamazaki, Shin

AU - Kishi, Reiko

AU - Yaegashi, Nobuo

AU - Hashimoto, Koichi

AU - Mori, Chisato

AU - Ito, Shuichi

AU - Yamagata, Zentaro

AU - Inadera, Hidekuni

AU - Nakayama, Takeo

AU - Sobue, Tomotaka

AU - Shima, Masayuki

AU - Nakamura, Hiroshige

AU - Suganuma, Narufumi

AU - Kusuhara, Koichi

AU - Katoh, Takahiko

N1 - Funding Information: This general birth cohort was a national, multicentre, prospective study: the Japan Environment and Children's Study (JECS) funded by the Ministry of the Environment, Japan. We enrolled a general population of 103,060 pregnancies and 51,239 pregnancies with participating fathers from January 2011 to March 2014. Eligibility criteria were as follows: (1) currently pregnant; (2) living in the Study Area for the foreseeable future; (3) expected delivery between 1 August 2011 and mid‐2014; and (4) ability to understand the Japanese language. In total, 104,062 records/foetal records were enrolled in the JECS. Caregivers answered questionnaires regarding their child and family during pregnancy and children aged 1, 6 and 18 months. We extracted medical chart information related to the prenatal period. For maternal medication use during the prenatal period, we had an interview face to face during the pregnancy. The study Programme Office performed the data management. The present study used the fixed data set “jecs‐ta‐201901930,” released in October 2019, including medical record transcriptions data, laboratory data and questionnaire data. The registry of the JECS is the University Hospital Medical Information Network (UMIN000030786). The JECS was conducted based on the Ethical Guidelines for Medical and Health Research Involving Human Subjects in Japan. The JECS protocol was released and approved by the Ministry of the Environment's Institutional Review Board on Epidemiological studies and the Ethics Committees of all participating institutions (no. 100910001). We obtained written informed consent from all participants. 4 Funding Information: We are grateful to all participants who have taken part in the JECS. We would like to also thank all staff members of the JECS. This study was funded by the Ministry of the Environment, Japan. The findings and conclusions of this article are solely the responsibility of the authors and do not represent the official views of the aforementioned government.

PY - 2023

Y1 - 2023

UR - http://www.scopus.com/inward/record.url?scp=85147008784&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85147008784&partnerID=8YFLogxK

U2 - 10.1111/cea.14286

DO - 10.1111/cea.14286

M3 - Letter

C2 - 36680339

AN - SCOPUS:85147008784

SN - 0954-7894

JO - Clinical and Experimental Allergy

JF - Clinical and Experimental Allergy

ER -