Preoperative Use of Tolvaptan in a Patient with Constrictive Pericarditis

Satoshi Kawatsu, Shingo Takahara, Kou Sakatsume, Keisuke Kanda, Tomoyuki Suzuki, Shintaro Katahira, Hidenori Fujiwara, Osamu Adachi, Masatoshi Akiyama, Kiichiro Kumagai, Shunsuke Kawamoto, Yoshikatsu Saiki

Research output: Contribution to journalArticlepeer-review


Tolvaptan is a new selective vasopression V2-receptor antagonist. We report our experience with a use of tolvaptan for preoperative fluid management in a patient with severe constrictive pericarditis. A 66-year-old man presented with heart failure symptoms derived from constrictive pericarditis. Chest X-ray showed right pleural effusion and chest computed tomography demonstrated severe pericardial calcification. Despite that he received optimal conventional medical treatments, his hemodynamic condition further exacerbated during hospitalization. We administered tolvaptan in an attempt to optimize preoperative fluid management. Tolvaptan was found to be remarkably effective in that regard. The body weight decreased and the heart failure symptoms improved. Pericardiectomy was performed successfully, and he recovered uneventfully.

Original languageEnglish
Pages (from-to)121-125
Number of pages5
JournalKyobu geka. The Japanese journal of thoracic surgery
Issue number2
Publication statusPublished - 2016 Feb 1


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