TY - JOUR
T1 - Preparation and molecular recognition of cyclodextrin monolayers with different cavity size on a gold wire electrode
AU - Suzuki, Iwao
AU - Murakami, Kazufumi
AU - Anzai, Jun Ichi
AU - Osa, Tetsuo
AU - He, Pingang
AU - Fang, Yuzhi
PY - 1998/9/1
Y1 - 1998/9/1
N2 - α-, β-, and γ-cyclodextrins (CyDs) bearing a lipoylamide residue (LP-α-CyD, LP-β-CyD, and LP-γ-CyD, respectively) at their primary hydroxyl sides were chemisorbed on a gold wire electrode. Charges associated with reductive desorption waves on cyclic voltammograms (CVs) observed for the modified electrodes revealed that the surface coverage of the CyD derivatives was nearly 100% or even higher, when the CyD derivatives were chemisorbed from their 1.0 X 10-3 M solutions. Surface plasmon resonance spectroscopy was applied to estimate the thickness of the LP-β-CyD adsorbed layer, indicating that the membrane would be a monolayer. Cyclic voltammetric studies on the monolayers of LP-CyDs using ferrocenecarboxylic acid (FCA) as an electroactive marker in 0.1 M H2SO4 solutions showed that FCA permeation was effectively blocked by the LP-α-CyD monolayer, while the CyD cavities in the LP-β-CyD and LP-γ-CyD monolayers made FCA permeate through the CyD monolayers. The molecular permeability was further checked by co-addition of electroinactive guests, assessed by the reduction in the anodic peak current of FCA.
AB - α-, β-, and γ-cyclodextrins (CyDs) bearing a lipoylamide residue (LP-α-CyD, LP-β-CyD, and LP-γ-CyD, respectively) at their primary hydroxyl sides were chemisorbed on a gold wire electrode. Charges associated with reductive desorption waves on cyclic voltammograms (CVs) observed for the modified electrodes revealed that the surface coverage of the CyD derivatives was nearly 100% or even higher, when the CyD derivatives were chemisorbed from their 1.0 X 10-3 M solutions. Surface plasmon resonance spectroscopy was applied to estimate the thickness of the LP-β-CyD adsorbed layer, indicating that the membrane would be a monolayer. Cyclic voltammetric studies on the monolayers of LP-CyDs using ferrocenecarboxylic acid (FCA) as an electroactive marker in 0.1 M H2SO4 solutions showed that FCA permeation was effectively blocked by the LP-α-CyD monolayer, while the CyD cavities in the LP-β-CyD and LP-γ-CyD monolayers made FCA permeate through the CyD monolayers. The molecular permeability was further checked by co-addition of electroinactive guests, assessed by the reduction in the anodic peak current of FCA.
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U2 - 10.1016/S0928-4931(98)00031-9
DO - 10.1016/S0928-4931(98)00031-9
M3 - Article
AN - SCOPUS:0032172951
SN - 0928-4931
VL - 6
SP - 19
EP - 25
JO - Materials Science and Engineering C
JF - Materials Science and Engineering C
IS - 1
ER -