TY - JOUR
T1 - Preparation of bioactive PDMS-modified CaO-SiO2-TiO2 hybrids by the sol-gel method
AU - Chen, Q.
AU - Kamitakahara, M.
AU - Miyata, N.
AU - Kokubo, T.
AU - Nakamura, T.
N1 - Funding Information:
This work was supported by Special Coordination Fund of the Science and Technology Agency of Japan, Research on Creation of Biointegrated Materials to Improve Physically Handicapped People’s Quality of Life.
PY - 2000/12
Y1 - 2000/12
N2 - Much attention has been focused on the development of a new type of bioactive material with mechanical properties analogous to those of natural bone. The present authors previously showed that some polydimethylsiloxane (PDMS)-modified CaO-SiO2-TiO2 hybrids prepared by sol-gel method show apatite-forming ability in a simulated body fluid (SBF), which is indicative of bioactivity. In the present study, effects of composition of PDMS-modified CaO-SiO2-TiO2 hybrids on their bioactivity and mechanical properties were investigated. The bioactivity of the hybrids increased with decreasing PDMS content and increasing TiO2 content. Their strain at failure increased with increasing PDMS content and decreasing TiO2 content. Some samples showed high bioactivity, as well as analogous mechanical properties to those of human cancellous bones. This type of hybrids might be useful as a bone-repairing material.
AB - Much attention has been focused on the development of a new type of bioactive material with mechanical properties analogous to those of natural bone. The present authors previously showed that some polydimethylsiloxane (PDMS)-modified CaO-SiO2-TiO2 hybrids prepared by sol-gel method show apatite-forming ability in a simulated body fluid (SBF), which is indicative of bioactivity. In the present study, effects of composition of PDMS-modified CaO-SiO2-TiO2 hybrids on their bioactivity and mechanical properties were investigated. The bioactivity of the hybrids increased with decreasing PDMS content and increasing TiO2 content. Their strain at failure increased with increasing PDMS content and decreasing TiO2 content. Some samples showed high bioactivity, as well as analogous mechanical properties to those of human cancellous bones. This type of hybrids might be useful as a bone-repairing material.
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U2 - 10.1023/A:1008774524468
DO - 10.1023/A:1008774524468
M3 - Conference article
AN - SCOPUS:0034476365
SN - 0928-0707
VL - 19
SP - 101
EP - 105
JO - Journal of Sol-Gel Science and Technology
JF - Journal of Sol-Gel Science and Technology
IS - 1-3
T2 - 10th International Workshop pn Glass and Ceramics, Hybrids and Nanocomposites from Gels
Y2 - 20 September 1999 through 24 September 1999
ER -