Preparation of powdered fish oil as a sustained-release formulation

Shigeta Aoki; Kiyotaka Nakagawa; Yasuhiko Hanzawa; Shunsuke Matsumoto; Mitsuaki Akutsu; Norihito Kimizuka; Makoto Shimoyamada; Masazumi Nishikawa; Teruo Miyazawa

doi:10.3136/nskkk.61.467

Preparation of powdered fish oil as a sustained-release formulation

Shigeta Aoki, Kiyotaka Nakagawa, Yasuhiko Hanzawa, Shunsuke Matsumoto, Mitsuaki Akutsu, Norihito Kimizuka, Makoto Shimoyamada, Masazumi Nishikawa, Teruo Miyazawa

New Industry Creation Hatchery Center (NICHe)

Research output: Contribution to journal › Article › peer-review

Abstract

Focusing on the gelatin/transglutaminase cross-linking reaction, we aimed to develop a preparation method for powdered fish oil as a sustained-release formulation. Various combinations of gelatin (containing transglutaminase) and emulsifiers were screened to obtain a high quality powder. The newly developed powder contained high amounts of lipids (74% of dry weight; 152mg docosahexaenoic acid/g, 41mg eicosapentaenoic acid/g); nevertheless, the powder exhibited good oxidation stability. As expected, the powdered fish oil showed slow-release properties in experiments in vitro. This novel powdered fish oil would therefore be useful for nutraceutical applications.

Original language	English
Pages (from-to)	467-474
Number of pages	8
Journal	Nippon Shokuhin Kagaku Kogaku Kaishi
Volume	61
Issue number	10
DOIs	https://doi.org/10.3136/nskkk.61.467
Publication status	Published - 2014

Keywords

DHA
EPA
Powdered fish oil
Slow-release property

ASJC Scopus subject areas

Food Science

Access to Document

10.3136/nskkk.61.467

Cite this

@article{1d38bee2608b44109254d88efa40ddda,

title = "Preparation of powdered fish oil as a sustained-release formulation",

abstract = "Focusing on the gelatin/transglutaminase cross-linking reaction, we aimed to develop a preparation method for powdered fish oil as a sustained-release formulation. Various combinations of gelatin (containing transglutaminase) and emulsifiers were screened to obtain a high quality powder. The newly developed powder contained high amounts of lipids (74% of dry weight; 152mg docosahexaenoic acid/g, 41mg eicosapentaenoic acid/g); nevertheless, the powder exhibited good oxidation stability. As expected, the powdered fish oil showed slow-release properties in experiments in vitro. This novel powdered fish oil would therefore be useful for nutraceutical applications.",

keywords = "DHA, EPA, Powdered fish oil, Slow-release property",

author = "Shigeta Aoki and Kiyotaka Nakagawa and Yasuhiko Hanzawa and Shunsuke Matsumoto and Mitsuaki Akutsu and Norihito Kimizuka and Makoto Shimoyamada and Masazumi Nishikawa and Teruo Miyazawa",

year = "2014",

doi = "10.3136/nskkk.61.467",

language = "English",

volume = "61",

pages = "467--474",

journal = "Nippon Shokuhin Kagaku Kogaku Kaishi",

issn = "1341-027X",

publisher = "Japanese Society for Food Science and Technology",

number = "10",

}

TY - JOUR

T1 - Preparation of powdered fish oil as a sustained-release formulation

AU - Aoki, Shigeta

AU - Nakagawa, Kiyotaka

AU - Hanzawa, Yasuhiko

AU - Matsumoto, Shunsuke

AU - Akutsu, Mitsuaki

AU - Kimizuka, Norihito

AU - Shimoyamada, Makoto

AU - Nishikawa, Masazumi

AU - Miyazawa, Teruo

PY - 2014

Y1 - 2014

N2 - Focusing on the gelatin/transglutaminase cross-linking reaction, we aimed to develop a preparation method for powdered fish oil as a sustained-release formulation. Various combinations of gelatin (containing transglutaminase) and emulsifiers were screened to obtain a high quality powder. The newly developed powder contained high amounts of lipids (74% of dry weight; 152mg docosahexaenoic acid/g, 41mg eicosapentaenoic acid/g); nevertheless, the powder exhibited good oxidation stability. As expected, the powdered fish oil showed slow-release properties in experiments in vitro. This novel powdered fish oil would therefore be useful for nutraceutical applications.

AB - Focusing on the gelatin/transglutaminase cross-linking reaction, we aimed to develop a preparation method for powdered fish oil as a sustained-release formulation. Various combinations of gelatin (containing transglutaminase) and emulsifiers were screened to obtain a high quality powder. The newly developed powder contained high amounts of lipids (74% of dry weight; 152mg docosahexaenoic acid/g, 41mg eicosapentaenoic acid/g); nevertheless, the powder exhibited good oxidation stability. As expected, the powdered fish oil showed slow-release properties in experiments in vitro. This novel powdered fish oil would therefore be useful for nutraceutical applications.

KW - DHA

KW - EPA

KW - Powdered fish oil

KW - Slow-release property

UR - http://www.scopus.com/inward/record.url?scp=84915809852&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84915809852&partnerID=8YFLogxK

U2 - 10.3136/nskkk.61.467

DO - 10.3136/nskkk.61.467

M3 - Article

AN - SCOPUS:84915809852

SN - 1341-027X

VL - 61

SP - 467

EP - 474

JO - Nippon Shokuhin Kagaku Kogaku Kaishi

JF - Nippon Shokuhin Kagaku Kogaku Kaishi

IS - 10

ER -

Preparation of powdered fish oil as a sustained-release formulation

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this