Pressure controlled clamp using shape memory alloy for minimal vessel invasion in blood flow occlusion

Ye Zhang, Hiroyasu Kanetaka, Yuya Sano, Mitsuhiro Kano, Tadaaki Kudo, Takumi Sato, Yoshinaka Shimizu

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)


Purpose: Vessel damage after clamping may affect the success of surgical operations. A new pressure controlled clamp (SMA clamp) was designed using super elastic property of shape memory alloy (SMA) to realize atraumatic vessel occlusion. The ability and biological effect of the SMA clamp to control pressure was investigated in vivo. Methods: The loading-displacement curves of the SMA clamps (experimental group) and conventional clamp (control group) by occlusion of pig carotid arteries were evaluated using a clamping-pressure analyzing system. To investigate macroscopically and histologically the vessel damage of the SMA and conventional clamps, pig carotid arteries were stained with Evan's blue and its histological sections were stained with Elastica Massion after clamping for fifteen minutes. Results: Constant value was shown in the loading-displacement curve of SMA clamp. In the control group, damaged area stained with Evan's blue in the vessel wall showed enlargement with the pressure increasing. Less areas in experimental groups are observed than that in the control group. Histological section in the experimental group showed no obvious except a slight compressive damage in the tunica intima. In the control group, vessel wall showed irreversible damages. Conclusions: This experiment indicated that the SMA clamp, which has a unique mechanical property, can be used without vessels damage. This pressure controlled clamp can be a selection in clinical apparatus to improve surgical safety.

Original languageEnglish
Pages (from-to)35-42
Number of pages8
JournalAnnals of Thoracic and Cardiovascular Surgery
Issue number1
Publication statusPublished - 2013


  • Clamp
  • Pressure control
  • Shape memory alloy
  • Vessel damage


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