Background and Objective: Various extrapulmonary effects and comorbidities have been noted to contribute to the burden of chronic obstructive pulmonary disease (COPD). However, the relationship between the prevalence of COPD and non-respiratory diseases has not been well investigated. The aim of the present study was to determine whether or not COPD is different among patients already suffering from other diseases. Methods: Spirometry was performed by patients aged ≥ 40 years old with non-respiratory diseases who visitect primary care clinics. Four hundred eighty-one patients performed spirometry and 7 patients were excluded because of poor spirometry maneuvers, resulting in 474 patients that were eligible for the current study. In subjects showing abnormalities in their spirograms, precise diagnoses were made using a questionnaire and chest X- ray examination. Results: Among the 474 patients, airflow limitation (FEV,/FVC<70%) was observed in 53 patients (11.2%). Forty-nine patients (10.3%) were diagnosed as COPD and 4 patients (0.8%) as bronchial asthma. Among the various diseases, the prevalence of COPD was significantly higher only in the patients with liver diseases, which was 18.8% (12 of 64 patients). The odds, ratio adjusted by both the amount of smoking and age was 2.66 (95%CI 1.06-6.63, p=0.037). Conclusions: The prevalence of COPD was different according to the type of disease, and patients with liver diseases had a higher prevalence of COPD.
- Liver disease