Production of 92Y via the 92Zr(n, p) reaction using the C(d, n) accelerator neutron source

Tadahiro Kin; Yukimasa Sanzen; Masaki Kamida; Yukinobu Watanabe; Masatoshi Itoh

doi:10.1051/epjconf/201714608009

Production of ⁹²Y via the ⁹²Zr(n, p) reaction using the C(d, n) accelerator neutron source

Tadahiro Kin, Yukimasa Sanzen, Masaki Kamida, Yukinobu Watanabe, Masatoshi Itoh

Cyclotron and Radioisotope Center (CYRIC)

Kyushu University

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Abstract

We have proposed a new method of producing medical radioisotope ⁹²Y as a candidate of alternatives of ¹¹¹In bioscan prior to ⁹⁰Y ibritumomab tiuxetan treatment. The ⁹²Y isotope is produced via the ⁹²Zr (n,p) reaction using accelerator neutrons generated by the interaction of deuteron beams with carbon. A feasibility experiment was performed at Cyclotron and Radioisotope Center, Tohoku University. A carbon thick target was irradiated by 20-MeV deuterons to produce accelerator neutrons. The thick target neutron yield (TTNY) was measured by using the multiple foils activation method. The foils were made of Al, Fe, Co, Ni, Zn, Zr, Nb, and Au. The production amount of ⁹²Y and induced impurities were estimated by simulation with the measured TTNY and the JENDL-4.0 nuclear data.

Original language	English
Title of host publication	ND 2016
Subtitle of host publication	International Conference on Nuclear Data for Science and Technology
Editors	Peter Siegler, Wim Mondelaers, Arjan Plompen, Franz-Josef Hambsch, Peter Schillebeeckx, Stefan Kopecky, Jan Heyse, Stephan Oberstedt
Publisher	EDP Sciences
ISBN (Electronic)	9782759890200
DOIs	https://doi.org/10.1051/epjconf/201714608009
Publication status	Published - 2017 Sept 13
Event	2016 International Conference on Nuclear Data for Science and Technology, ND 2016 - Bruges, Belgium Duration: 2016 Sept 11 → 2016 Sept 16

Publication series

Name	EPJ Web of Conferences
Volume	146
ISSN (Print)	2101-6275
ISSN (Electronic)	2100-014X

Conference

Conference	2016 International Conference on Nuclear Data for Science and Technology, ND 2016
Country/Territory	Belgium
City	Bruges
Period	16/9/11 → 16/9/16

Access to Document

10.1051/epjconf/201714608009

Cite this

Kin, T., Sanzen, Y., Kamida, M., Watanabe, Y., & Itoh, M. (2017). Production of ⁹²Y via the ⁹²Zr(n, p) reaction using the C(d, n) accelerator neutron source. In P. Siegler, W. Mondelaers, A. Plompen, F-J. Hambsch, P. Schillebeeckx, S. Kopecky, J. Heyse, & S. Oberstedt (Eds.), ND 2016: International Conference on Nuclear Data for Science and Technology Article 08009 (EPJ Web of Conferences; Vol. 146). EDP Sciences. https://doi.org/10.1051/epjconf/201714608009

Kin, Tadahiro ; Sanzen, Yukimasa ; Kamida, Masaki et al. / Production of ⁹²Y via the ⁹²Zr(n, p) reaction using the C(d, n) accelerator neutron source. ND 2016: International Conference on Nuclear Data for Science and Technology. editor / Peter Siegler ; Wim Mondelaers ; Arjan Plompen ; Franz-Josef Hambsch ; Peter Schillebeeckx ; Stefan Kopecky ; Jan Heyse ; Stephan Oberstedt. EDP Sciences, 2017. (EPJ Web of Conferences).

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title = "Production of 92Y via the 92Zr(n, p) reaction using the C(d, n) accelerator neutron source",

abstract = "We have proposed a new method of producing medical radioisotope 92Y as a candidate of alternatives of 111In bioscan prior to 90Y ibritumomab tiuxetan treatment. The 92Y isotope is produced via the 92Zr (n,p) reaction using accelerator neutrons generated by the interaction of deuteron beams with carbon. A feasibility experiment was performed at Cyclotron and Radioisotope Center, Tohoku University. A carbon thick target was irradiated by 20-MeV deuterons to produce accelerator neutrons. The thick target neutron yield (TTNY) was measured by using the multiple foils activation method. The foils were made of Al, Fe, Co, Ni, Zn, Zr, Nb, and Au. The production amount of 92Y and induced impurities were estimated by simulation with the measured TTNY and the JENDL-4.0 nuclear data.",

author = "Tadahiro Kin and Yukimasa Sanzen and Masaki Kamida and Yukinobu Watanabe and Masatoshi Itoh",

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Kin, T, Sanzen, Y, Kamida, M, Watanabe, Y & Itoh, M 2017, Production of ⁹²Y via the ⁹²Zr(n, p) reaction using the C(d, n) accelerator neutron source. in P Siegler, W Mondelaers, A Plompen, F-J Hambsch, P Schillebeeckx, S Kopecky, J Heyse & S Oberstedt (eds), ND 2016: International Conference on Nuclear Data for Science and Technology., 08009, EPJ Web of Conferences, vol. 146, EDP Sciences, 2016 International Conference on Nuclear Data for Science and Technology, ND 2016, Bruges, Belgium, 16/9/11. https://doi.org/10.1051/epjconf/201714608009

Production of ⁹²Y via the ⁹²Zr(n, p) reaction using the C(d, n) accelerator neutron source. / Kin, Tadahiro; Sanzen, Yukimasa; Kamida, Masaki et al.
ND 2016: International Conference on Nuclear Data for Science and Technology. ed. / Peter Siegler; Wim Mondelaers; Arjan Plompen; Franz-Josef Hambsch; Peter Schillebeeckx; Stefan Kopecky; Jan Heyse; Stephan Oberstedt. EDP Sciences, 2017. 08009 (EPJ Web of Conferences; Vol. 146).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

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AU - Kin, Tadahiro

AU - Sanzen, Yukimasa

AU - Kamida, Masaki

AU - Watanabe, Yukinobu

AU - Itoh, Masatoshi

N1 - Publisher Copyright: © The Authors, published by EDP Sciences, 2017.

PY - 2017/9/13

Y1 - 2017/9/13

N2 - We have proposed a new method of producing medical radioisotope 92Y as a candidate of alternatives of 111In bioscan prior to 90Y ibritumomab tiuxetan treatment. The 92Y isotope is produced via the 92Zr (n,p) reaction using accelerator neutrons generated by the interaction of deuteron beams with carbon. A feasibility experiment was performed at Cyclotron and Radioisotope Center, Tohoku University. A carbon thick target was irradiated by 20-MeV deuterons to produce accelerator neutrons. The thick target neutron yield (TTNY) was measured by using the multiple foils activation method. The foils were made of Al, Fe, Co, Ni, Zn, Zr, Nb, and Au. The production amount of 92Y and induced impurities were estimated by simulation with the measured TTNY and the JENDL-4.0 nuclear data.

AB - We have proposed a new method of producing medical radioisotope 92Y as a candidate of alternatives of 111In bioscan prior to 90Y ibritumomab tiuxetan treatment. The 92Y isotope is produced via the 92Zr (n,p) reaction using accelerator neutrons generated by the interaction of deuteron beams with carbon. A feasibility experiment was performed at Cyclotron and Radioisotope Center, Tohoku University. A carbon thick target was irradiated by 20-MeV deuterons to produce accelerator neutrons. The thick target neutron yield (TTNY) was measured by using the multiple foils activation method. The foils were made of Al, Fe, Co, Ni, Zn, Zr, Nb, and Au. The production amount of 92Y and induced impurities were estimated by simulation with the measured TTNY and the JENDL-4.0 nuclear data.

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Kin T, Sanzen Y, Kamida M, Watanabe Y, Itoh M. Production of ⁹²Y via the ⁹²Zr(n, p) reaction using the C(d, n) accelerator neutron source. In Siegler P, Mondelaers W, Plompen A, Hambsch F-J, Schillebeeckx P, Kopecky S, Heyse J, Oberstedt S, editors, ND 2016: International Conference on Nuclear Data for Science and Technology. EDP Sciences. 2017. 08009. (EPJ Web of Conferences). doi: 10.1051/epjconf/201714608009