Prognostic value of home heart rate for cardiovascular mortality in the general population: The Ohasama study

Atsushi Hozawa, Takayoshi Ohkubo, Masahiro Kikuya, Takashi Ugajin, Junko Yamaguchi, Kei Asayama, Hirohito Metoki, Kaori Ohmori, Haruhisa Hoshi, Junichiro Hashimoto, Hiroshi Satoh, Ichiro Tsuji, Yutaka Imai

Research output: Contribution to journalArticlepeer-review

82 Citations (Scopus)


Recently, the advantages of self-measurement of blood pressure (BP) at home have been recognized. The same advantages could also be applicable to resting heart rate (HR) values assessed at home using a device designed for home BP measurement. However, there have been no studies investigating whether home HR values predict the risk of cardiovascular disease mortality. We therefore investigated the usefulness of HR values in predicting cardiovascular mortality using a device that allowed self-measurement of BP and HR at home. The association between the home-measured resting HR and the 10-year risk of cardiovascular mortality was examined in 1780 Japanese individuals ≥40 years of age who had no significant arrhythmias. A Cox proportional hazards model that adjusted for major risk factors was used. An increase of 5 beats/min in the morning home HR measurement was associated with a 17% increase in the risk of cardiovascular mortality (95% confidence interval 5% to 30%). This relationship was also statistically significant after adjustment for home BP values. Even when home-measured systolic BP was within the normal range (<135 mm Hg), subjects with HR ≥70 beats/min had a higher risk of cardiovascular mortality (relative hazard 2.16, 95% confidence interval 1.21 to 3.85) than those with normal systolic BP and HR values. Self-measurement of HR at home, together with self-measurement of BP, is a simple method of providing useful clinical information for assessing cardiovascular risk.

Original languageEnglish
Pages (from-to)1005-1010
Number of pages6
JournalAmerican Journal of Hypertension
Issue number11
Publication statusPublished - 2004 Nov


  • Heart rate
  • blood pressure
  • cardiovascular disease
  • mortality
  • population

ASJC Scopus subject areas

  • Internal Medicine


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