Proliferation and adhesion of periodontal ligament cells on synthetic biominerals

Junko Hatakeyama; Yuji Hatakeyama; Ichiro Takahashi; Osamu Suzuki; Yasuyuki Sasano

doi:10.1016/j.ics.2005.06.089

Proliferation and adhesion of periodontal ligament cells on synthetic biominerals

Junko Hatakeyama, Yuji Hatakeyama, Ichiro Takahashi, Osamu Suzuki, Yasuyuki Sasano

DEN - Dental Sciences

Research output: Contribution to journal › Review article › peer-review

Abstract

The present study was designed to investigate the proliferation and expression of adhesion and extracellular matrix molecules in periodontal ligament (PDL) cells cultured on synthetic calcium phosphates, octacalcium phosphate and its hydrolyzed apatitic product comparing with those cultured on collagen and plastic substrates. Our results suggest that PDL cells expressing various integrins are attached to the synthetic biomineral analogues through collagens and fibronectin produced by themselves. These calcium phosphates relevant to biomineralization may support proliferation and adhesion of PDL cells in vivo.

Original language	English
Pages (from-to)	328-329
Number of pages	2
Journal	International Congress Series
Volume	1284
DOIs	https://doi.org/10.1016/j.ics.2005.06.089
Publication status	Published - 2005 Sept

Keywords

Cell adhesion
Integrin
Periodontal ligament
RGD
Synthetic biominerals

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10.1016/j.ics.2005.06.089

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title = "Proliferation and adhesion of periodontal ligament cells on synthetic biominerals",

abstract = "The present study was designed to investigate the proliferation and expression of adhesion and extracellular matrix molecules in periodontal ligament (PDL) cells cultured on synthetic calcium phosphates, octacalcium phosphate and its hydrolyzed apatitic product comparing with those cultured on collagen and plastic substrates. Our results suggest that PDL cells expressing various integrins are attached to the synthetic biomineral analogues through collagens and fibronectin produced by themselves. These calcium phosphates relevant to biomineralization may support proliferation and adhesion of PDL cells in vivo.",

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author = "Junko Hatakeyama and Yuji Hatakeyama and Ichiro Takahashi and Osamu Suzuki and Yasuyuki Sasano",

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T1 - Proliferation and adhesion of periodontal ligament cells on synthetic biominerals

AU - Hatakeyama, Junko

AU - Hatakeyama, Yuji

AU - Takahashi, Ichiro

AU - Suzuki, Osamu

AU - Sasano, Yasuyuki

PY - 2005/9

Y1 - 2005/9

N2 - The present study was designed to investigate the proliferation and expression of adhesion and extracellular matrix molecules in periodontal ligament (PDL) cells cultured on synthetic calcium phosphates, octacalcium phosphate and its hydrolyzed apatitic product comparing with those cultured on collagen and plastic substrates. Our results suggest that PDL cells expressing various integrins are attached to the synthetic biomineral analogues through collagens and fibronectin produced by themselves. These calcium phosphates relevant to biomineralization may support proliferation and adhesion of PDL cells in vivo.

AB - The present study was designed to investigate the proliferation and expression of adhesion and extracellular matrix molecules in periodontal ligament (PDL) cells cultured on synthetic calcium phosphates, octacalcium phosphate and its hydrolyzed apatitic product comparing with those cultured on collagen and plastic substrates. Our results suggest that PDL cells expressing various integrins are attached to the synthetic biomineral analogues through collagens and fibronectin produced by themselves. These calcium phosphates relevant to biomineralization may support proliferation and adhesion of PDL cells in vivo.

KW - Cell adhesion

KW - Integrin

KW - Periodontal ligament

KW - RGD

KW - Synthetic biominerals

UR - http://www.scopus.com/inward/record.url?scp=33646460930&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33646460930&partnerID=8YFLogxK

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DO - 10.1016/j.ics.2005.06.089

M3 - Review article

AN - SCOPUS:33646460930

SN - 0531-5131

VL - 1284

SP - 328

EP - 329

JO - International Congress Series

JF - International Congress Series

ER -

Proliferation and adhesion of periodontal ligament cells on synthetic biominerals

Abstract

Keywords

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