TY - JOUR
T1 - Pure topographical disorientation in novel environments without anterograde amnesia
T2 - a case study
AU - Oishi, Yuka
AU - Yamakawa, Tatsushi
AU - Nagasawa, Hikaru
AU - Suzuki, Kyoko
N1 - Funding Information:
This work was supported by a Grant-in-Aid for Scientific Research (C) [No. 17K01480] from MEXT to YO, Japan, a Grant from Niigata University of Health and Welfare [No. H30C07] to YO, Japan, and a Grant-in-Aid for Scientific Research on Innovative Areas from MEXT [No. 15H05915, No. 17H05936] to KS, Japan. We thank the participants of this study. We also thank Dr. Kazuyo Tanji and Dr. Naohiro Saito for their helpful suggestions regarding earlier versions of this paper. This work was supported by a Grant-in-Aid for Scientific Research (No. 17K01480) and Grant from Niigata University of Health and Welfare (No. H30C07) to YO and a Grant-in-Aid for Scientific Research on Innovative Areas from MEXT (No. 15H05915, No.17H05936) to KS. Lastly, we are tremendously grateful to the patient and her family for their support.
Publisher Copyright:
© 2019, © 2019 Informa UK Limited, trading as Taylor & Francis Group.
PY - 2019/9/3
Y1 - 2019/9/3
N2 - Topographical disorientation (TD) in novel environments is considered to be a part of anterograde amnesia. A 56-year-old woman presented with pure TD only in novel environments following limbic encephalitis. She could not remember directions inside the hospital on weekly outpatient visits; however, her verbal and visual anterograde memories were normal. In the test of learning photographs of scenes, faces, and objects, only her scores for landscapes were worse than those in healthy controls. These findings suggested that her TD specific to landscapes and directions in novel environments was caused by category-specific memory impairment related to bilateral hippocampal and parahippocampal dysfunction.
AB - Topographical disorientation (TD) in novel environments is considered to be a part of anterograde amnesia. A 56-year-old woman presented with pure TD only in novel environments following limbic encephalitis. She could not remember directions inside the hospital on weekly outpatient visits; however, her verbal and visual anterograde memories were normal. In the test of learning photographs of scenes, faces, and objects, only her scores for landscapes were worse than those in healthy controls. These findings suggested that her TD specific to landscapes and directions in novel environments was caused by category-specific memory impairment related to bilateral hippocampal and parahippocampal dysfunction.
KW - directional disorientation
KW - hippocampal gyrus
KW - landmark agnosia
KW - parahippocampal gyrus
KW - Topographical disorientation
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U2 - 10.1080/13554794.2019.1642359
DO - 10.1080/13554794.2019.1642359
M3 - Article
C2 - 31298073
AN - SCOPUS:85068936510
SN - 1355-4794
VL - 25
SP - 177
EP - 186
JO - Neurocase
JF - Neurocase
IS - 5
ER -