Radiofrequency ablation of the liver: Determination of ablative margin at MR imaging with impaired clearance of ferucarbotran - Feasibility study

Kensaku Mori; Kuniaki Fukuda; Hitoshi Asaoka; Takuya Ueda; Akira Kunimatsu; Yoshikazu Okamoto; Katsuhiro Nasu; Kiyoshi Fukunaga; Yukio Morishita; Manabu Minami

doi:10.1148/radiol.2512081161

Radiofrequency ablation of the liver: Determination of ablative margin at MR imaging with impaired clearance of ferucarbotran - Feasibility study

Kensaku Mori, Kuniaki Fukuda, Hitoshi Asaoka, Takuya Ueda, Akira Kunimatsu, Yoshikazu Okamoto, Katsuhiro Nasu, Kiyoshi Fukunaga, Yukio Morishita, Manabu Minami

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Abstract

Institutional review board approval and informed consent were obtained. The feasibility of magnetic resonance (MR) imaging with impaired clearance of ferucarbotran to visualize ablated liver parenchyma surrounding a tumor (ablative margin [AM]) was evaluated after radiofrequency (RF) ablation of the liver. Twenty-one patients with hepatocellular carcinomas underwent RF ablation 2-7 hours after ferucarbotran-enhanced MR imaging. On unenhanced T2*-weighted images acquired after 3-5 days, AMs appeared as hypointense rims. The AM status was related to incidence of residual or recurrent tumors. This technique is feasible for visualization of AM and prediction of residual or recurrent tumors after RF ablation of the liver.

Original language	English
Pages (from-to)	557-565
Number of pages	9
Journal	Radiology
Volume	251
Issue number	2
DOIs	https://doi.org/10.1148/radiol.2512081161
Publication status	Published - 2009 May 1
Externally published	Yes

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

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abstract = "Institutional review board approval and informed consent were obtained. The feasibility of magnetic resonance (MR) imaging with impaired clearance of ferucarbotran to visualize ablated liver parenchyma surrounding a tumor (ablative margin [AM]) was evaluated after radiofrequency (RF) ablation of the liver. Twenty-one patients with hepatocellular carcinomas underwent RF ablation 2-7 hours after ferucarbotran-enhanced MR imaging. On unenhanced T2*-weighted images acquired after 3-5 days, AMs appeared as hypointense rims. The AM status was related to incidence of residual or recurrent tumors. This technique is feasible for visualization of AM and prediction of residual or recurrent tumors after RF ablation of the liver.",

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AU - Mori, Kensaku

AU - Fukuda, Kuniaki

AU - Asaoka, Hitoshi

AU - Ueda, Takuya

AU - Kunimatsu, Akira

AU - Okamoto, Yoshikazu

AU - Nasu, Katsuhiro

AU - Fukunaga, Kiyoshi

AU - Morishita, Yukio

AU - Minami, Manabu

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Y1 - 2009/5/1

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Radiofrequency ablation of the liver: Determination of ablative margin at MR imaging with impaired clearance of ferucarbotran - Feasibility study

Abstract

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