Randomized controlled trial of a water-soluble formulation of lutein in humans

Junya Kobayashi, Etsuko Tominaga, Makoto Ozeki, Tsutomu Okubo, Kiyotaka Nakagawa, Teruo Miyazawa

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)

Abstract

Lutein is poorly absorbed owing to their high hydrophobicity and crystallinity. This double-blind crossover trial involved eight healthy males who were administrated capsules containing either a lutein water-soluble formulation or a lutein oil suspension for 8 days. In the formulation group, plasma and erythrocytes lutein concentrations and baseline-corrected AUC were two-fold higher than those in the oil suspension group.

Original languageEnglish
Pages (from-to)2372-2374
Number of pages3
JournalBioscience, Biotechnology and Biochemistry
Volume83
Issue number12
DOIs
Publication statusPublished - 2019

Keywords

  • Bioavailability
  • Formulation
  • Lutein

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