Ratchet model of motor proteins and its energetics

Yohei Nakayama; Eiro Muneyuki

doi:10.1007/978-981-10-8459-1_14

Ratchet model of motor proteins and its energetics

Yohei Nakayama, Eiro Muneyuki

ENG - Applied Physics

Chuo University

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Abstract

We describe the energetics of motor proteins by taking F₁ -ATPase as an example. To clarify the meaning of the mechanical works which are experimentally measured, we first identify the heat, which satisfies the second law of thermodynamics, and next formulate the work through the first law of thermodynamics. The theoretical expressions of the mechanical works reveal that the experimentally measured works have a theoretical basis. Contrary to the mechanical work, the measurement of the heat is still developing. We introduce an attempt to measure a part of the heat, which is related to the experimentally accessible quantities through a nonequilibrium equality.

Original language	English
Title of host publication	The Role of Water in ATP Hydrolysis Energy Transduction by Protein Machinery
Publisher	Springer Singapore
Pages	231-243
Number of pages	13
ISBN (Electronic)	9789811084591
ISBN (Print)	9789811084584
DOIs	https://doi.org/10.1007/978-981-10-8459-1_14
Publication status	Published - 2018 May 7

Keywords

First and second laws of thermodynamics
Motor protein
Nonequilibrium system
Single-molecule experiment

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10.1007/978-981-10-8459-1_14

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Ratchet model of motor proteins and its energetics

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