We describe the energetics of motor proteins by taking F1 -ATPase as an example. To clarify the meaning of the mechanical works which are experimentally measured, we first identify the heat, which satisfies the second law of thermodynamics, and next formulate the work through the first law of thermodynamics. The theoretical expressions of the mechanical works reveal that the experimentally measured works have a theoretical basis. Contrary to the mechanical work, the measurement of the heat is still developing. We introduce an attempt to measure a part of the heat, which is related to the experimentally accessible quantities through a nonequilibrium equality.
|Title of host publication||The Role of Water in ATP Hydrolysis Energy Transduction by Protein Machinery|
|Number of pages||13|
|Publication status||Published - 2018 May 7|
- First and second laws of thermodynamics
- Motor protein
- Nonequilibrium system
- Single-molecule experiment