Rationale behind the design and comparative evaluation of an all-in-one self-etch model adhesive

Masafumi Kanehira, Werner J. Finger, Hiroshi Ishihata, Marcus Hoffmann, Atsufumi Manabe, Hidetoshi Shimauchi, Masashi Komatsu

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)


Objective: To investigate and compare bonding and dentin sealing efficacy of a marketed all-in-one and an experimental model adhesive with minimum effective amounts of acidic monomer and water. Materials and methods: Composition of model adhesive (NAD) in mass%: UDMA (45), 4-META (20), H2O (7.5), and acetone (27.5). For characterization of a reasonable NAD application procedure shear bond strengths (SBS, n = 8) were determined on human enamel and dentin. Clearfil S3 Bond (TSB; Kuraray) served as reference. SBSs were evaluated after 10 min, 1 and 7 days, and 1 month, marginal adaptation (n = 8) was assessed in cylindrical butt-joint dentin cavities. Diffusive and convective water fluxes through 1 mm thick adhesive-coated dentin disks (n = 6) were qualitatively and quantitatively analyzed. Results: SBSs proved that application of NAD in one coat with 20 s agitated dwell time was ≥20 MPa, enamel SBSs (24 h) were 25 MPa, p > 0.05. Dentin SBSs for TSB and NAD were not different (p > 0.05) at the four stages (means: 18.9, 23.5, 25.4, and 23.6 MPa). Five and seven of the eight bonded restorations with TSB and NAD were gap-free (p > 0.05). Dentin disks treated with EDTA from both sides or one side only were highly permeable for liquid, whereas adhesive-coated dentin disks showed no permeability at 0 and 2.5 kPa water pressure. Conclusions: Within the limitations of this study the model adhesive tested represents a promising basic composition for all-in-one adhesives, eliminating common problems encountered with single step adhesives such as phase separation and permeability.

Original languageEnglish
Pages (from-to)432-439
Number of pages8
JournalJournal of Dentistry
Issue number6
Publication statusPublished - 2009 Jun 1


  • Bond strength
  • Enamel-dentin bonding
  • Marginal adaptation
  • Permeability
  • Phase separation
  • Self-etch adhesives

ASJC Scopus subject areas

  • Dentistry(all)


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