Refractory In-Stent Restenosis Attributable to Eruptive Calcified Nodule

Hiroki Nakano, Yu Kataoka, Fumiyuki Otsuka, Takahiro Nakashima, Yasuhide Asaumi, Teruo Noguchi, Satoshi Yasuda

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)


A 75-year-old female patient on hemodialysis presented with non–ST-segment elevation myocardial infarction. After successful primary percutaneous coronary intervention, in-stent restenosis (ISR) occurred 3 consecutive times. Intravascular imaging assessment during the repeated percutaneous coronary intervention indicated that the ISR was not associated with neointimal hyperplasia but was mainly attributed to a calcified nodule, which protruded into the lumen. We applied excimer laser catheter ablation to avoid another ISR. (Level of Difficulty: Intermediate.)

Original languageEnglish
Pages (from-to)1872-1878
Number of pages7
JournalJACC: Case Reports
Issue number12
Publication statusPublished - 2020 Oct


  • calcified nodule
  • in-stent restenosis
  • intravascular imaging
  • percutaneous coronary intervention


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