A systematic investigation of reductive ring expansion reaction of oximes with diisobutylaluminum hydride (DIBAH) was performed. The reaction regiospecifically provided a variety of unsubstituted bicyclic heterocycles 3a-3g or tricyclic heterocycles 3h, 3j-3l that contained nitrogen attached to an aromatic ring.
- Diisobutylaluminum Hydride (DIBAH)
- Regiospecitic Synthesis
- Ring Expansion
- Unsubstituted Basic Skeleton