TY - JOUR
T1 - Relations of mold, stove, and fragrance products on childhood wheezing and asthma
T2 - A prospective cohort study from the Japan Environment and Children's Study
AU - Saijo, Yasuaki
AU - Yoshioka, Eiji
AU - Sato, Yukihiro
AU - Azuma, Hiroshi
AU - Tanahashi, Yusuke
AU - Ito, Yoshiya
AU - Kobayashi, Sumitaka
AU - Minatoya, Machiko
AU - Ait Bamai, Yu
AU - Yamazaki, Keiko
AU - Itoh, Sachiko
AU - Miyashita, Chihiro
AU - Ikeda-Araki, Atsuko
AU - Kishi, Reiko
AU - Kamijima, Michihiro
AU - Yamazaki, Shin
AU - Ohya, Yukihiro
AU - Yaegashi, Nobuo
AU - Hashimoto, Koichi
AU - Mori, Chisato
AU - Ito, Shuichi
AU - Yamagata, Zentaro
AU - Inadera, Hidekuni
AU - Nakayama, Takeo
AU - Iso, Hiroyasu
AU - Shima, Masayuki
AU - Kurozawa, Youichi
AU - Suganuma, Narufumi
AU - Kusuhara, Koichi
AU - Katoh, Takahiko
N1 - Funding Information:
The Japan Environment and Children's Study was funded by the Ministry of Environment, Japan. The findings and conclusions of this article are solely the responsibility of the authors and do not represent the official views of the above government We would like to express our gratitude to all participants of the JECS and all staff members involved in data collection. We would like to thank Editage (www.editage.com) for English language editing.
Funding Information:
The Japan Environment and Children's Study was funded by the Ministry of Environment, Japan. The findings and conclusions of this article are solely the responsibility of the authors and do not represent the official views of the above government
Publisher Copyright:
© 2021 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd
PY - 2022/1
Y1 - 2022/1
N2 - This prospective cohort study aimed to examine the associations between mold growth, type of stoves, and fragrance materials and early childhood wheezing and asthma, using data from the Japan Environment and Children's Study. Mold growth at home, usage of kerosene/gas stove, wood stove/fireplace, and air freshener/deodorizer were surveyed using a questionnaire at 1.5-year-old, and childhood wheezing and doctor-diagnosed asthma during the previous year were obtained using a 3-year-old questionnaire. Multilevel logistic regression analysis was performed to evaluate the association between exposure to childhood wheezing and asthma. A total of 60 529 children were included in the analysis. In multivariate analyses, mold growth and wood stove/fireplace had significantly higher odds ratios (ORs) for wheezing (mold growth: 1.13; 95% CI, 1.06−1.22; wood stove/fireplace: 1.23; 95% CI, 1.03−1.46). All four exposures had no significant ORs for childhood doctor-diagnosed asthma; however, in the supplemental analysis of northern regions, wood stove/fireplace had a significantly higher OR for asthma. Mold growth and wood stove/fireplace had significant associations with childhood wheezing in the northern regions. Mold elimination in the dwellings and use of clean heating (no air pollution emissions) should be taken into consideration to prevent and improve childhood wheezing and asthma.
AB - This prospective cohort study aimed to examine the associations between mold growth, type of stoves, and fragrance materials and early childhood wheezing and asthma, using data from the Japan Environment and Children's Study. Mold growth at home, usage of kerosene/gas stove, wood stove/fireplace, and air freshener/deodorizer were surveyed using a questionnaire at 1.5-year-old, and childhood wheezing and doctor-diagnosed asthma during the previous year were obtained using a 3-year-old questionnaire. Multilevel logistic regression analysis was performed to evaluate the association between exposure to childhood wheezing and asthma. A total of 60 529 children were included in the analysis. In multivariate analyses, mold growth and wood stove/fireplace had significantly higher odds ratios (ORs) for wheezing (mold growth: 1.13; 95% CI, 1.06−1.22; wood stove/fireplace: 1.23; 95% CI, 1.03−1.46). All four exposures had no significant ORs for childhood doctor-diagnosed asthma; however, in the supplemental analysis of northern regions, wood stove/fireplace had a significantly higher OR for asthma. Mold growth and wood stove/fireplace had significant associations with childhood wheezing in the northern regions. Mold elimination in the dwellings and use of clean heating (no air pollution emissions) should be taken into consideration to prevent and improve childhood wheezing and asthma.
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U2 - 10.1111/ina.12931
DO - 10.1111/ina.12931
M3 - Article
C2 - 34773308
AN - SCOPUS:85118957550
SN - 0905-6947
VL - 32
JO - Indoor Air
JF - Indoor Air
IS - 1
M1 - e12931
ER -
