TY - JOUR
T1 - Relationship between litter size at birth and within-litter birth weight characteristics in laboratory mice as pilot animal for pig
AU - Ogawa, Shinichiro
AU - Satoh, Masahiro
N1 - Funding Information:
We thank Akiko Iwai, Kazuyuki Tashima, Ayane Konta, Ryoichi Furukawa, Natsumi Yazaki, Tomohiro Ishizaka, Kasumi Ichinoseki, Yusuke Ota, Hitomi Hara, Taiga Ito, Suguru Kitajima, and Chihiro Homma, a technical assistant and students of the Laboratory of Animal Breeding and Genetics, Graduate School of Agricultural Science, Tohoku University, for their help in data collection. We thank Yuki Arino and Nana Sato, technical staffs of the Animal experiment building of the Graduate School of Agricultural Science, for maintaining the rearing room.
Publisher Copyright:
© 2020 Japanese Society of Animal Science
PY - 2020/1/1
Y1 - 2020/1/1
N2 - We investigated the relationship between litter size at birth and within-litter birth weight (BW) characteristics of laboratory mice as a pilot mammal for pig. We obtained records of number born alive (NBA) and total and mean litter BW (LWB, MWB), and maximum and minimum values of within-litter BW (MaxIWB, MinIWB), range and standard deviation (Range, SDIWB), skewness (Skew), and kurtosis (Kurt) of within-litter BW for 656 litters at first parity. Pearson's correlations of NBA were highly positive with LWB (0.92), weakly negative with MWB (–0.31), MaxIWB (–0.19), and MinIBW (–0.33), and those of MWB were negligible with Range, SDIWB, Skew, and Kurt (–0.10 to 0.06). Estimated heritabilities, treated as dam traits, were 0.32 for NBA, 0.39 for LWB, 0.24 for MWB, 0.28 for MaxIWB, 0.05 for MinIWB, 0.16 for Range, 0.17 for SDIWB, and 0.00 for Skew and Kurt. Estimated genetic correlation between NBA and LWB was high (0.95). Therefore, LWB could be promising for efficiently improving NBA. The estimated genetic correlation of NBA was negligible with MWB (0.00), positive with MaxIWB (0.10), Range (0.48), and SDIWB (0.36), and negative with MinIWB (–0.36), suggesting that selection for increased NBA brings larger SDIWB and lighter MinIWB.
AB - We investigated the relationship between litter size at birth and within-litter birth weight (BW) characteristics of laboratory mice as a pilot mammal for pig. We obtained records of number born alive (NBA) and total and mean litter BW (LWB, MWB), and maximum and minimum values of within-litter BW (MaxIWB, MinIWB), range and standard deviation (Range, SDIWB), skewness (Skew), and kurtosis (Kurt) of within-litter BW for 656 litters at first parity. Pearson's correlations of NBA were highly positive with LWB (0.92), weakly negative with MWB (–0.31), MaxIWB (–0.19), and MinIBW (–0.33), and those of MWB were negligible with Range, SDIWB, Skew, and Kurt (–0.10 to 0.06). Estimated heritabilities, treated as dam traits, were 0.32 for NBA, 0.39 for LWB, 0.24 for MWB, 0.28 for MaxIWB, 0.05 for MinIWB, 0.16 for Range, 0.17 for SDIWB, and 0.00 for Skew and Kurt. Estimated genetic correlation between NBA and LWB was high (0.95). Therefore, LWB could be promising for efficiently improving NBA. The estimated genetic correlation of NBA was negligible with MWB (0.00), positive with MaxIWB (0.10), Range (0.48), and SDIWB (0.36), and negative with MinIWB (–0.36), suggesting that selection for increased NBA brings larger SDIWB and lighter MinIWB.
KW - birth weight
KW - genetic parameter estimation
KW - laboratory mice
KW - litter size at birth
KW - pig
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U2 - 10.1111/asj.13488
DO - 10.1111/asj.13488
M3 - Article
C2 - 33222366
AN - SCOPUS:85096631327
SN - 1344-3941
VL - 91
JO - Animal Science Journal
JF - Animal Science Journal
IS - 1
M1 - e13488
ER -