Relationship between the combination of polyunsaturated fatty acids intake and psychological distress during pregnancy: The Tohoku medical megabank project birth and three-generation cohort study

I. Takahashi, T. Obara, M. Aizawa, Y. Yonezawa, F. Ueno, A. Noda, T. Onuma, F. Matsuzaki, K. Murakami, M. Ishikuro, S. Kuriyama

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

No studies have examined the association of the combination of n-3 polyunsaturated fatty acids (PUFAs) and n-6 PUFAs intake with psychological distress during pregnancy. To examine these associations, we divided Japanese pregnant women into 25 groups based on combining quintiles of n-3 PUFAs intake and quintiles of n-6 PUFAs intake. We conducted multivariable logistic regression analyses to assess the risk of psychological distress during pregnancy (Kessler Psychological Distress Scale ≥ 5 or 13). Compared to the third quintile of both n-3 PUFAs and n-6 PUFAs intake, the groups with unbalanced intake, high intake of both, and low intake of both were associated with a higher risk of both Kessler Psychological Distress Scale ≥ 5 and 13 in early and mid-pregnancy.

Original languageEnglish
Article number102400
JournalProstaglandins Leukotrienes and Essential Fatty Acids
Volume177
DOIs
Publication statusPublished - 2022 Feb

ASJC Scopus subject areas

  • Clinical Biochemistry
  • Cell Biology

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