Reproducibility of nocturnal blood pressure assessed by self-measurement of blood pressure at home

Keiko Hosohata, Masahiro Kikuya, Takayoshi Ohkubo, Hirohito Metoki, Kei Asayama, Ryusuke Inoue, Taku Obara, Junichiro Hashimoto, Kazuhito Totsune, Haruhisa Hoshi, Hiroshi Satoh, Yutaka Imai

Research output: Contribution to journalArticlepeer-review

40 Citations (Scopus)


To assess the reproducibility of nocturnal blood pressure (BP) during sleep as measured using a self-measurement device at home, we obtained repeated nocturnal home BP at 0200 h and quality of sleep assessment from a diary in 556 subjects (71% women, 62.4±11.1 years) in the general population. We used an Omron device (HEM-747IC-N, Omron Healthcare Co., Ltd., Kyoto, Japan), with which the time and frequency of monitoring can be preset and the readings stored. The mean±SD of the difference between test-retest BP measurements was 0.7±15.1 mmHg systolic and 0.2±9.7 mmHg diastolic with a mean interval of 5.9 days. The absolute differences were greater than 10 mmHg in 261 (46.9%) subjects for systolic and 145 (26.0%) subjects for diastolic. There was no evidence of regression to the mean in nocturnal measurements over at least three nights (n=390, p>0.22). The differences (the first minus the second measurement) were large in subjects who experienced sleep disturbance only in the first (n=64, 2.3±13.6 mmHg and 1.6±9.6 mmHg for systolic and diastolic, respectively) or second sessions (n=56, -4.1±16.4 mmHg and -2.5±11.4 mmHg) compared with the subjects without sleep disturbance (n=66, 1.5±17.8 mmHg and 0.8±10.3 mmHg) and those with sleep disturbance (n=370, 0.9±14.5 mmHg and 0.2±9.3 mmHg) in both sessions. In conclusion, the reproducibility of single nocturnal BP as assessed using a self-measurement device at home was not good, especially for subjects who experienced different quality of sleep in each session. To evaluate nocturnal BP using a self-measurement device, estimation of quality of sleep is indispensable.

Original languageEnglish
Pages (from-to)707-712
Number of pages6
JournalHypertension Research
Issue number8
Publication statusPublished - 2007 Aug


  • General population
  • Nocturnal blood pressure
  • Omron HEM-7471C-N
  • Reproducibility
  • Self measurement


Dive into the research topics of 'Reproducibility of nocturnal blood pressure assessed by self-measurement of blood pressure at home'. Together they form a unique fingerprint.

Cite this