Resolution of inherently chiral anti-O,O′-dialkylthiacalix[4]arenes and determination of their absolute stereochemistries

Fumitaka Narumi, Nobuji Matsumura, Nariaki Sasagawa, Koichi Natori, Takashi Kajiwara, Tetsutaro Hattori

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)

Abstract

Inherently chiral anti-O,O′-dibenzyl- and anti-O,O′-dibutyl-p-tert-butylthiacalix[4]arenes 4 and 6 are resolved as (S)-2-methoxy-2-(naphthalen-1-yl)propionic esters by flash chromatography. The absolute stereochemistries were determined to be (Sa)-(+)-4 and (Sa)-(+)-6 by X-ray crystallographic analyses.

Original languageEnglish
Pages (from-to)1470-1475
Number of pages6
JournalTetrahedron Asymmetry
Volume19
Issue number12
DOIs
Publication statusPublished - 2008 Jun 30

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