Secondary Amyloidosis Associated with Castleman's Disease

Katsuhiro Tanaka, Masakazu Horita, Hitoshi Shibayama, Masataka Seike, Yasuko Itoh, Kazuyuki Hamaguchi, Yasufumi Sato, Toshiie Sakata, Tetsuya Ishida

Research output: Contribution to journalArticlepeer-review

25 Citations (Scopus)


A rare case of secondary amyloidosis associated with Castleman's disease is reported. A 53-year-old woman was referred for investigation of proteinuria. Biopsy specimens from kidney and gastric mucosa revealed numerous amyloid deposits, denned as AA amyloidosis by immunohistological staining. Castleman's disease was found in the abdomen as the primary disease for the amyloidosis. Although the urinary protein was somewhat reduced and the inflammatory findings were improved after removal of the lymphoma, renal insufficiency progressed and hemodialysis was begun.

Original languageEnglish
Pages (from-to)122-126
Number of pages5
JournalInternal Medicine
Issue number2
Publication statusPublished - 1995


  • renal insufficiency
  • serum amyloid protein A


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