TY - JOUR
T1 - Selective cerebral perfusion with the open proximal technique during descending thoracic or thoracoabdominal aortic repair
T2 - An option of choice to reduce neurologic complications
AU - Hosoyama, Katsuhiro
AU - Kawamoto, Shunsuke
AU - Kumagai, Kiichiro
AU - Akiyama, Masatoshi
AU - Adachi, Osamu
AU - Kawatsu, Satoshi
AU - Saiki, Yoshikatsu
N1 - Publisher Copyright:
© 2018 The Editorial Committee of Annals of Thoracic and Cardiovascular Surgery. All rights reserved.
PY - 2018
Y1 - 2018
N2 - Purpose: Selective cerebral perfusion with the open proximal technique for thoracoabdominal aortic repair has not been conclusively validated because of its procedural complexity and unreliability. We report the clinical outcomes, particularly the cere-broneurological complications, of an open proximal procedure using selective cerebral perfusion. Methods: A retrospective chart review identified 30 patients between 2007 and 2015 who underwent aortic repair through left lateral thoracotomy with selective cerebral perfusion, established through endoluminal brachiocephalic and left carotid artery and retrograde left axillary artery. Results: The mean durations of the open proximal procedure and cerebral ischemia (the duration of the open proximal procedure minus the duration of selective cerebral perfu-sion) were 110.3 ± 40.1 min and 24.8 ± 13.0 min, respectively. There were two cases (7%) of permanent neurologic dysfunction (PND) but no in-hospital deaths. Multivariate analysis identified the duration of cerebral ischemia as an independent risk factor for neurologic complications including temporary neurologic dysfunction (TND; odds ratio (OR): 1.13; p = 0.007), but no correlation was found between selective cerebral perfusion duration and neurologic complications. Conclusion: Despite the relatively long duration of the open proximal procedure, selective cerebral perfusion has a potential to protect against cerebral complications during thoracic aortic repair through a left lateral thoracotomy.
AB - Purpose: Selective cerebral perfusion with the open proximal technique for thoracoabdominal aortic repair has not been conclusively validated because of its procedural complexity and unreliability. We report the clinical outcomes, particularly the cere-broneurological complications, of an open proximal procedure using selective cerebral perfusion. Methods: A retrospective chart review identified 30 patients between 2007 and 2015 who underwent aortic repair through left lateral thoracotomy with selective cerebral perfusion, established through endoluminal brachiocephalic and left carotid artery and retrograde left axillary artery. Results: The mean durations of the open proximal procedure and cerebral ischemia (the duration of the open proximal procedure minus the duration of selective cerebral perfu-sion) were 110.3 ± 40.1 min and 24.8 ± 13.0 min, respectively. There were two cases (7%) of permanent neurologic dysfunction (PND) but no in-hospital deaths. Multivariate analysis identified the duration of cerebral ischemia as an independent risk factor for neurologic complications including temporary neurologic dysfunction (TND; odds ratio (OR): 1.13; p = 0.007), but no correlation was found between selective cerebral perfusion duration and neurologic complications. Conclusion: Despite the relatively long duration of the open proximal procedure, selective cerebral perfusion has a potential to protect against cerebral complications during thoracic aortic repair through a left lateral thoracotomy.
KW - Aortic repair
KW - Circulatory arrest
KW - Neuroprotection
KW - Open proximal procedure
KW - Selective cerebral perfusion
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U2 - 10.5761/atcs.oa.17-00138
DO - 10.5761/atcs.oa.17-00138
M3 - Article
C2 - 29375096
AN - SCOPUS:85045841932
SN - 1341-1098
VL - 24
SP - 89
EP - 96
JO - Annals of Thoracic and Cardiovascular Surgery
JF - Annals of Thoracic and Cardiovascular Surgery
IS - 2
ER -