Low-temperature scanning tunnelling microscopy (LT-STM), surface acoustic wave (SAW), and mechanical cantilever are used to measure and manipulate quantum characteristics in semiconductor heterostructures. A nanoscale detection of local density of states is demonstrated for electrons confined in semiconductor quantum wells and dots by a combination of InAs-based heterostructures and LT-STM. The SAW is used to realize moving quantum wires and dots in semiconductor heterostructures. A synchronized optical measurement confirms two types of modulation, i.e. bandgap and potential modulations. A combination of mechanical cantilever and quantum heterostructures gives a new mechanical functionality and a novel tool to analyse quantum transport characteristics.