Sentinel lymph node biopsy with a handheld cordless magnetic probe following preoperative MR lymphography using superparamagnetic iron oxide for clinically N0 early oral cancer: A feasibility study

Satomi Sugiyama, Toshinori Iwai, Junichi Baba, Senri Oguri, Toshiharu Izumi, Akihiro Kuwahata, Masaki Sekino, Moriaki Kusakabe, Kenji Mitsudo

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)

Abstract

Purpose: Radioisotope (RI) tracers are generally used for preoperative mapping of sentinel lymph node (SLN) and intraoperative detection with a portable γ probe. However, the use of RI has several limitations. Therefore, a method without RI is required for the widespread application of SLN biopsy. The purpose of this study was to evaluate the feasibility of SLN biopsy with a handheld cordless magnetic probe following magnetic resonance lymphography (MRL) using superparamagnetic iron oxide (SPIO) and for clinically N0 early oral cancer. Materials and methods: MRL using SPIO and SLNB with the handheld cordless magnetic probe were performed for 27 patients with clinically N0 early oral cancer. Results: In all 27 patients (100%), SLNs were detected by MRL, and the total and mean number of SLNs were 73 and 2.7, respectively. All SLNs identified by MRL were detectable using the magnetic probe in all patients. Conclusions: SLNB with handheld cordless magnetic probe following preoperative SLN mapping by MRL using SPIO is feasible, without RI use, for neck management in cases of clinically N0 early oral cancer.

Original languageEnglish
Pages (from-to)521-526
Number of pages6
JournalJournal of Stomatology, Oral and Maxillofacial Surgery
Volume123
Issue number5
DOIs
Publication statusPublished - 2022 Oct

Keywords

  • Early oral cancer
  • Magnetic probe
  • Magnetic resonance lymphography
  • Sentinel lymph node
  • Sentinel lymph node biopsy
  • Superparamagnetic iron oxide

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