TY - JOUR
T1 - Similarity in Amplitude of the Nocturnal fall in Blood Pressure in Old and Young Patients with Essential Hypertension
AU - Nihei, Minoru
AU - Imai, Yutaka
AU - Abe, Keishi
AU - Sasaki, Shuichi
AU - Minami, Naoyoshi
AU - Munakata, Masanori
AU - Sakuma, Hiromichi
AU - Hashimoto, Junichiro
AU - Yoshinaga, Kaoru
AU - Sekino, Hiroshi
PY - 1989
Y1 - 1989
N2 - The influence of age on the nocturnal fall in blood pressure (BP) was examined in essential hypertensive patients as well as normal subjects. BP was monitored every 5 min for 24 hr by means of a finger volume oscillometric device. Average daytime BP was similar in the 3 age groups [young : <40 (years), n=49, average daytime systolic BP (ASBP)=132±20 mmHg, average daytime diastolic BP (ADBP)= 82 ± 17 mmHg ; adult : 40≤ <60, n =110, ASBP =127 ± 19 mmHg, ADBP = 86 ± 13 mmHg ; old : 60≤, n=33, ASBP =131 ± 17 mmHg. ADBP = 83 ± 11, mean ± s.d.]. The nocturnal fall in BP was observed in all age groups and its amplitude (d B P = average daytime B P - average nighttime BP) in the old patients (ΔSBP = 13±11 mmHg, ΔDBP=10+8 mmHg) was similar to that in the young patients (ΔSBP=11±8 mmHg, ΔDBP=10±8 mmHg). The result suggests that information on the nocturnal behavior of BP is valuable in treating aged essential hypertensives to prevent cerebral and/or myocardial ischemia during sleep.
AB - The influence of age on the nocturnal fall in blood pressure (BP) was examined in essential hypertensive patients as well as normal subjects. BP was monitored every 5 min for 24 hr by means of a finger volume oscillometric device. Average daytime BP was similar in the 3 age groups [young : <40 (years), n=49, average daytime systolic BP (ASBP)=132±20 mmHg, average daytime diastolic BP (ADBP)= 82 ± 17 mmHg ; adult : 40≤ <60, n =110, ASBP =127 ± 19 mmHg, ADBP = 86 ± 13 mmHg ; old : 60≤, n=33, ASBP =131 ± 17 mmHg. ADBP = 83 ± 11, mean ± s.d.]. The nocturnal fall in BP was observed in all age groups and its amplitude (d B P = average daytime B P - average nighttime BP) in the old patients (ΔSBP = 13±11 mmHg, ΔDBP=10+8 mmHg) was similar to that in the young patients (ΔSBP=11±8 mmHg, ΔDBP=10±8 mmHg). The result suggests that information on the nocturnal behavior of BP is valuable in treating aged essential hypertensives to prevent cerebral and/or myocardial ischemia during sleep.
KW - age
KW - ambulatory blood pressure monitoring
KW - circadian rhythm
KW - essential hypertension
KW - nocturnal fall in blood pressure
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U2 - 10.1620/tjem.158.163
DO - 10.1620/tjem.158.163
M3 - Article
C2 - 2772919
AN - SCOPUS:0024448703
SN - 0040-8727
VL - 158
SP - 163
EP - 169
JO - Tohoku Journal of Experimental Medicine
JF - Tohoku Journal of Experimental Medicine
IS - 2
ER -