Simple primary β-amino alcohols as organocatalysts for the asymmetric Michael addition of β-keto esters to nitroalkenes

Zubeda Begum; Haruka Sannabe; Chigusa Seki; Yuko Okuyama; Eunsang Kwon; Koji Uwai; Michio Tokiwa; Suguru Tokiwa; Mitsuhiro Takeshita; Hiroto Nakano

doi:10.1039/d0ra09041g

Simple primary β-amino alcohols as organocatalysts for the asymmetric Michael addition of β-keto esters to nitroalkenes

Zubeda Begum, Haruka Sannabe, Chigusa Seki, Yuko Okuyama, Eunsang Kwon, Koji Uwai, Michio Tokiwa, Suguru Tokiwa, Mitsuhiro Takeshita, Hiroto Nakano

SCI - Research and Analytical Center for Giant Molecules

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

Abstract

Simple primary β-amino alcohols act as an efficient organocatalysts in the asymmetric Michael addition of β-keto esters with nitroalkenes affording highly pure chiral Michael adducts. Also, both enantiomers of the adducts were obtained, depending on the specific catalyst used and reaction temperature.

Original language	English
Pages (from-to)	203-209
Number of pages	7
Journal	RSC Advances
Volume	11
Issue number	1
DOIs	https://doi.org/10.1039/d0ra09041g
Publication status	Published - 2020 Dec 3

ASJC Scopus subject areas

Chemistry(all)
Chemical Engineering(all)

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title = "Simple primary β-amino alcohols as organocatalysts for the asymmetric Michael addition of β-keto esters to nitroalkenes",

abstract = "Simple primary β-amino alcohols act as an efficient organocatalysts in the asymmetric Michael addition of β-keto esters with nitroalkenes affording highly pure chiral Michael adducts. Also, both enantiomers of the adducts were obtained, depending on the specific catalyst used and reaction temperature.",

author = "Zubeda Begum and Haruka Sannabe and Chigusa Seki and Yuko Okuyama and Eunsang Kwon and Koji Uwai and Michio Tokiwa and Suguru Tokiwa and Mitsuhiro Takeshita and Hiroto Nakano",

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T1 - Simple primary β-amino alcohols as organocatalysts for the asymmetric Michael addition of β-keto esters to nitroalkenes

AU - Begum, Zubeda

AU - Sannabe, Haruka

AU - Seki, Chigusa

AU - Okuyama, Yuko

AU - Kwon, Eunsang

AU - Uwai, Koji

AU - Tokiwa, Michio

AU - Tokiwa, Suguru

AU - Takeshita, Mitsuhiro

AU - Nakano, Hiroto

PY - 2020/12/3

Y1 - 2020/12/3

N2 - Simple primary β-amino alcohols act as an efficient organocatalysts in the asymmetric Michael addition of β-keto esters with nitroalkenes affording highly pure chiral Michael adducts. Also, both enantiomers of the adducts were obtained, depending on the specific catalyst used and reaction temperature.

AB - Simple primary β-amino alcohols act as an efficient organocatalysts in the asymmetric Michael addition of β-keto esters with nitroalkenes affording highly pure chiral Michael adducts. Also, both enantiomers of the adducts were obtained, depending on the specific catalyst used and reaction temperature.

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DO - 10.1039/d0ra09041g

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JF - RSC Advances

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ER -

Simple primary β-amino alcohols as organocatalysts for the asymmetric Michael addition of β-keto esters to nitroalkenes

Abstract

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