Simulation of atrial wall suction in a continuous flow total artificial heart model

Paul S. Olegario, Makoto Yoshizawa, Akira Tanaka, Daisuke Ogawa, Yasuyuki Shiraishi, Tomoyuki Yambe, Shin Ichi Nitta

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review


An existing mathematical model of the cardiovascular system was modified by replacing the ventricles of the natural heart with two rotary blood pumps to investigate the problem of atrial wall suction in a continuous flow total artificial heart system and provide preliminary data for the implementation of an anti-suction control algorithm with quicker response. The responses of left atrial pressure to changes in right pump output were investigated through computer simulations using the modified model. The results were then compared with actual data from a prior acute animal experiment with a healthy mature goat performed to obtain data on pulmonary circulation dynamics and to determine the conditions that lead to atrial wall suction. The simulation results showed significant agreement with the animal experiment data with regards to left atrial pressure response to changes in right pump speed. Atrial wall suction was also successfully simulated using this model.

Original languageEnglish
Title of host publication2006 SICE-ICASE International Joint Conference
Number of pages4
Publication statusPublished - 2006
Event2006 SICE-ICASE International Joint Conference - Busan, Korea, Republic of
Duration: 2006 Oct 182006 Oct 21

Publication series

Name2006 SICE-ICASE International Joint Conference


Conference2006 SICE-ICASE International Joint Conference
Country/TerritoryKorea, Republic of


  • Artificial heart
  • Cardiovascular model
  • Simulation


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