@article{86f58c1f375d48f5bc45590ba4eee865,
title = "Sodium Phenoxide Mediated Hydroxymethylation of Alkynylsilanes with N-[(Trimethylsiloxy)methyl]phthalimide",
abstract = "The hydroxymethylation of alkynylsilanes with formaldehyde generated in situ from N-[(trimethylsiloxy)methyl]phthalimide proceeds in the presence of a stoichiometric amount of NaOPh. The reaction occurs at room temperature by using an operationally simple one-step procedure. A variety of alkynylsilanes possessing electron-donating, electron-withdrawing, and halogen groups (including heteroaryl-substituted alkynylsilanes) provide hydroxymethylated products.",
keywords = "C1 building blocks, Hydroxymethylation, Lewis bases, Organosilanes, Silicates",
author = "Narumi Asano and Keita Sasaki and Isabelle Chataigner and Masanori Shigeno and Yoshinori Kondo",
note = "Funding Information: This work was financially supported by the Japan Society for the Promotion of Science (JSPS) KAKENHI Grant no. 23105009 in Advanced Molecular Transformations by Organocatalysis (Y. K.), KAKENHI Grant no. 16H00997 in Precisely Designed Catalysts with Customized Scaffolding (Y. K.), and KAKENHI Grant no. 17K15419 (M. S.). This work was also supported by the Platform Project for Supporting Drug Discovery and Life Science Research funded by the Japan Agency for Medical Research and Development (AMED) (Y. K. and M. S.). Publisher Copyright: {\textcopyright} 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim",
year = "2017",
month = dec,
day = "15",
doi = "10.1002/ejoc.201701440",
language = "English",
volume = "2017",
pages = "6926--6930",
journal = "Justus Liebigs Annalen der Chemie",
issn = "0075-4617",
publisher = "Wiley-VCH Verlag",
number = "46",
}