@inproceedings{2887d8c339224f74925e959b72ac0f04,
title = "Sprouting from on-chip vascular networks by a pressure-driven flow",
abstract = "We quantitatively evaluated how vascular networks reconstructed in a microfluidic device were remodeled under a pressure-driven flow. We fabricated a PDMS device, and co-cultured human umbilical vein endothelial cells (HUVECs) and normal human lung fibroblasts (hLFs) to spontaneously reconstruct vascular networks. After a pressure-driven flow (0-120 μL/h) was applied to the vascular networks for 24 hours, we found the number of angiogenic sprouting increasing with the increase of flow rate and perfusion time.",
keywords = "Angiogenic sprouting, Microfluidic device, Pressure-driven flow, Vascular network",
author = "Masamune Nakayama and Yuji Nashimoto and Itsuki Kunita and Akiko Nakamasu and Torisawa, {Yu Suke} and Hirofumi Shintaku and Hidetoshi Kotera and Koichi Nishiyama and Takashi Miura and Ryuji Yokokawa",
year = "2016",
language = "English",
series = "20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016",
publisher = "Chemical and Biological Microsystems Society",
pages = "429--430",
booktitle = "20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016",
note = "20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016 ; Conference date: 09-10-2016 Through 13-10-2016",
}