Stability of cerebral blood flow and oxygen metabolism during normal aging

Masatoshi Itoh; Jun Hatazawa; Hidemi Miyazawa; Hiroshi Matsui; Kenichi Meguro; Kazuhiko Yanai; Kazuo Kubota; Shoichi Watanuki; Tatsuo Ido; Taiju Matsuzawa

doi:10.1159/000213174

Stability of cerebral blood flow and oxygen metabolism during normal aging

Masatoshi Itoh, Jun Hatazawa, Hidemi Miyazawa, Hiroshi Matsui, Kenichi Meguro, Kazuhiko Yanai, Kazuo Kubota, Shoichi Watanuki, Tatsuo Ido, Taiju Matsuzawa

Tohoku University

Research output: Contribution to journal › Article › peer-review

43 Citations (Scopus)

Abstract

Cerebral blood flow and oxygen metabolism in aged normal subjects were measured with positron emission tomography and their relationship with brain atrophy was evaluated. Brain atrophy progressed in a linear fashion during aging while cerebral blood flow and oxygen metabolism were well preserved. The finding suggests that brain atrophy is an aging process less dependent on cerebral blood flow and metabolism over the course of normal aging.

Original language	English
Pages (from-to)	43-48
Number of pages	6
Journal	Gerontology
Volume	36
Issue number	1
DOIs	https://doi.org/10.1159/000213174
Publication status	Published - 1990

Keywords

Brain atrophy
Cerebral blood flow
Cerebral metabolism

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10.1159/000213174

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AU - Itoh, Masatoshi

AU - Hatazawa, Jun

AU - Miyazawa, Hidemi

AU - Matsui, Hiroshi

AU - Meguro, Kenichi

AU - Yanai, Kazuhiko

AU - Kubota, Kazuo

AU - Watanuki, Shoichi

AU - Ido, Tatsuo

AU - Matsuzawa, Taiju

PY - 1990

Y1 - 1990

N2 - Cerebral blood flow and oxygen metabolism in aged normal subjects were measured with positron emission tomography and their relationship with brain atrophy was evaluated. Brain atrophy progressed in a linear fashion during aging while cerebral blood flow and oxygen metabolism were well preserved. The finding suggests that brain atrophy is an aging process less dependent on cerebral blood flow and metabolism over the course of normal aging.

AB - Cerebral blood flow and oxygen metabolism in aged normal subjects were measured with positron emission tomography and their relationship with brain atrophy was evaluated. Brain atrophy progressed in a linear fashion during aging while cerebral blood flow and oxygen metabolism were well preserved. The finding suggests that brain atrophy is an aging process less dependent on cerebral blood flow and metabolism over the course of normal aging.

KW - Brain atrophy

KW - Cerebral blood flow

KW - Cerebral metabolism

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Stability of cerebral blood flow and oxygen metabolism during normal aging

Abstract

Keywords

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