Stabilization of small unilamellar liposomes: Polymerization of surfactants in phospholipid vesicles

Kazue Kurihara, Janos H. Fendler

Research output: Contribution to journalArticlepeer-review

Abstract

Cosonication of a styrene-containing surfactant H2C=CHC 6H4NHCO[CH2]10N+(C 16H33)Me2Br- (1) with dipalmitoylphosphatidylcholine (DPPC) leads to mixed DPPC-(1) 300 Å diameter unilamellar vesicles which subsequent to photopolymerization maintain their morphologies for months; conversely, nonpolymerized vesicles undergo spontaneous growth to 700 Å diameter vesicles.

Original languageEnglish
Pages (from-to)1188-1189
Number of pages2
JournalJournal of the Chemical Society, Chemical Communications
Issue number21
DOIs
Publication statusPublished - 1983 Jan 1
Externally publishedYes

ASJC Scopus subject areas

  • Molecular Medicine

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