Stereocontrolled total synthesis of (+)-vinblastine

Satoshi Yokoshima, Toshihiro Ueda, Satoshi Kobayashi, Ayato Sato, Takeshi Kuboyama, Hidetoshi Tokuyama, Tohru Fukuyama

Research output: Contribution to journalArticlepeer-review

224 Citations (Scopus)


A stereocontrolled total synthesis of (+)-vinblastine was accomplished, featuring preparations of the two indole units by means of a novel indole synthesis via radical cyclization of thioanilide, and a stereoselective coupling of these units.

Original languageEnglish
Pages (from-to)2137-2139
Number of pages3
JournalJournal of the American Chemical Society
Issue number10
Publication statusPublished - 2002 Mar 13


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