Stereoselective synthesis of functionalized (Z)-keto-enyne and its epoxide

S. Khan, N. Kato, M. Hirama

Research output: Contribution to journalArticlepeer-review

13 Citations (Scopus)


An efficient method to synthesize (Z)-keto-enyne and its epoxide, possible key intermediates in the total synthesis of maduropeptin chromophore, has been developed through a BuLi-mediated reductive opening of α-bromoepoxide.

Original languageEnglish
Pages (from-to)1494-1496
Number of pages3
Issue number10
Publication statusPublished - 2000


  • Enynes
  • Epoxides
  • Halides
  • Ring opening
  • Stereoselective synthesis

ASJC Scopus subject areas

  • Organic Chemistry


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