Stereoselective synthesis of substituted tetrahydropyrans via domino olefin cross-metathesis/intramolecular oxa-conjugate cyclization

Haruhiko Fuwa; Kenkichi Noto; Makoto Sasaki

doi:10.1021/ol100431m

Stereoselective synthesis of substituted tetrahydropyrans via domino olefin cross-metathesis/intramolecular oxa-conjugate cyclization

Haruhiko Fuwa, Kenkichi Noto, Makoto Sasaki

Research output: Contribution to journal › Article › peer-review

68 Citations (Scopus)

Abstract

(Figure Presented) A novel strategy for the stereoselective synthesis of substituted tetrahydropyrans has been developed on the basis of a domino olefin crossmetathesis/intramolecular oxa-conjugate cyclization catalyzed by the Hoveyda- Grubbs second-generation catalyst.

Original language	English
Pages (from-to)	1636-1639
Number of pages	4
Journal	Organic letters
Volume	12
Issue number	7
DOIs	https://doi.org/10.1021/ol100431m
Publication status	Published - 2010 Apr 2

ASJC Scopus subject areas

Biochemistry
Physical and Theoretical Chemistry
Organic Chemistry

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10.1021/ol100431m

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abstract = "(Figure Presented) A novel strategy for the stereoselective synthesis of substituted tetrahydropyrans has been developed on the basis of a domino olefin crossmetathesis/intramolecular oxa-conjugate cyclization catalyzed by the Hoveyda- Grubbs second-generation catalyst.",

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AU - Noto, Kenkichi

AU - Sasaki, Makoto

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N2 - (Figure Presented) A novel strategy for the stereoselective synthesis of substituted tetrahydropyrans has been developed on the basis of a domino olefin crossmetathesis/intramolecular oxa-conjugate cyclization catalyzed by the Hoveyda- Grubbs second-generation catalyst.

AB - (Figure Presented) A novel strategy for the stereoselective synthesis of substituted tetrahydropyrans has been developed on the basis of a domino olefin crossmetathesis/intramolecular oxa-conjugate cyclization catalyzed by the Hoveyda- Grubbs second-generation catalyst.

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Stereoselective synthesis of substituted tetrahydropyrans via domino olefin cross-metathesis/intramolecular oxa-conjugate cyclization

Abstract

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