Stereotactic body radiotherapy for pulmonary oligometastases from esophageal cancer: Results and prognostic factors

Takaya Yamamoto; Yuzuru Niibe; Yasuo Matsumoto; Yasuhiro Dekura; Ryoong Jin Oh; Hideomi Yamashita; Hisao Kakuhara; Masahiko Aoki; Keiichi Jingu

doi:10.21873/anticanres.14164

Stereotactic body radiotherapy for pulmonary oligometastases from esophageal cancer: Results and prognostic factors

Takaya Yamamoto, Yuzuru Niibe, Yasuo Matsumoto, Yasuhiro Dekura, Ryoong Jin Oh, Hideomi Yamashita, Hisao Kakuhara, Masahiko Aoki, Keiichi Jingu

Research output: Contribution to journal › Article › peer-review

10 Citations (Scopus)

Abstract

Background/Aim: The aim of this multi-center retrospective study was to investigate the results of stereotactic body radiotherapy (SBRT) for pulmonary oligometastases from esophageal cancer. Patients and Methods: Oligometastases from the esophagus were identified from a dataset of a Japanese survey. The Kaplan-Meier method and Cox regression were applied to perform analyses. Results: A total of 114 patients with 132 pulmonary oligometastases were collected. The 3-year local control rate, freedom from further metastasis (FFFM) rate and overall survival (OS) rate were 70.2%, 25.3% and 37.5%, respectively. Performance status (PS) (PS 1 vs. PS 0, p<0.01), disease-free interval (p=0.03) and history of local therapy for metastasis (p=0.01) had significant relationships with FFFM and only PS was an independent prognostic factor for OS (PS 1 vs. PS 0, p=0.02; PS 2-3 vs. PS 0, p=0.04). Conclusion: SBRT for pulmonary oligometastases from esophageal cancer provided good local control and survival.

Original language	English
Pages (from-to)	2065-2072
Number of pages	8
Journal	Anticancer Research
Volume	40
Issue number	4
DOIs	https://doi.org/10.21873/anticanres.14164
Publication status	Published - 2020 Apr

Keywords

Esophageal cancer
Oligo-recurrence
Oligometastases
Prognostic factor
Stereotactic body radiotherapy (SBRT)

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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title = "Stereotactic body radiotherapy for pulmonary oligometastases from esophageal cancer: Results and prognostic factors",

abstract = "Background/Aim: The aim of this multi-center retrospective study was to investigate the results of stereotactic body radiotherapy (SBRT) for pulmonary oligometastases from esophageal cancer. Patients and Methods: Oligometastases from the esophagus were identified from a dataset of a Japanese survey. The Kaplan-Meier method and Cox regression were applied to perform analyses. Results: A total of 114 patients with 132 pulmonary oligometastases were collected. The 3-year local control rate, freedom from further metastasis (FFFM) rate and overall survival (OS) rate were 70.2%, 25.3% and 37.5%, respectively. Performance status (PS) (PS 1 vs. PS 0, p<0.01), disease-free interval (p=0.03) and history of local therapy for metastasis (p=0.01) had significant relationships with FFFM and only PS was an independent prognostic factor for OS (PS 1 vs. PS 0, p=0.02; PS 2-3 vs. PS 0, p=0.04). Conclusion: SBRT for pulmonary oligometastases from esophageal cancer provided good local control and survival.",

keywords = "Esophageal cancer, Oligo-recurrence, Oligometastases, Prognostic factor, Stereotactic body radiotherapy (SBRT)",

author = "Takaya Yamamoto and Yuzuru Niibe and Yasuo Matsumoto and Yasuhiro Dekura and Oh, {Ryoong Jin} and Hideomi Yamashita and Hisao Kakuhara and Masahiko Aoki and Keiichi Jingu",

year = "2020",

month = apr,

doi = "10.21873/anticanres.14164",

language = "English",

volume = "40",

pages = "2065--2072",

journal = "Anticancer Research",

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publisher = "International Institute of Anticancer Research",

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}

TY - JOUR

T1 - Stereotactic body radiotherapy for pulmonary oligometastases from esophageal cancer

T2 - Results and prognostic factors

AU - Yamamoto, Takaya

AU - Niibe, Yuzuru

AU - Matsumoto, Yasuo

AU - Dekura, Yasuhiro

AU - Oh, Ryoong Jin

AU - Yamashita, Hideomi

AU - Kakuhara, Hisao

AU - Aoki, Masahiko

AU - Jingu, Keiichi

PY - 2020/4

Y1 - 2020/4

N2 - Background/Aim: The aim of this multi-center retrospective study was to investigate the results of stereotactic body radiotherapy (SBRT) for pulmonary oligometastases from esophageal cancer. Patients and Methods: Oligometastases from the esophagus were identified from a dataset of a Japanese survey. The Kaplan-Meier method and Cox regression were applied to perform analyses. Results: A total of 114 patients with 132 pulmonary oligometastases were collected. The 3-year local control rate, freedom from further metastasis (FFFM) rate and overall survival (OS) rate were 70.2%, 25.3% and 37.5%, respectively. Performance status (PS) (PS 1 vs. PS 0, p<0.01), disease-free interval (p=0.03) and history of local therapy for metastasis (p=0.01) had significant relationships with FFFM and only PS was an independent prognostic factor for OS (PS 1 vs. PS 0, p=0.02; PS 2-3 vs. PS 0, p=0.04). Conclusion: SBRT for pulmonary oligometastases from esophageal cancer provided good local control and survival.

AB - Background/Aim: The aim of this multi-center retrospective study was to investigate the results of stereotactic body radiotherapy (SBRT) for pulmonary oligometastases from esophageal cancer. Patients and Methods: Oligometastases from the esophagus were identified from a dataset of a Japanese survey. The Kaplan-Meier method and Cox regression were applied to perform analyses. Results: A total of 114 patients with 132 pulmonary oligometastases were collected. The 3-year local control rate, freedom from further metastasis (FFFM) rate and overall survival (OS) rate were 70.2%, 25.3% and 37.5%, respectively. Performance status (PS) (PS 1 vs. PS 0, p<0.01), disease-free interval (p=0.03) and history of local therapy for metastasis (p=0.01) had significant relationships with FFFM and only PS was an independent prognostic factor for OS (PS 1 vs. PS 0, p=0.02; PS 2-3 vs. PS 0, p=0.04). Conclusion: SBRT for pulmonary oligometastases from esophageal cancer provided good local control and survival.

KW - Esophageal cancer

KW - Oligo-recurrence

KW - Oligometastases

KW - Prognostic factor

KW - Stereotactic body radiotherapy (SBRT)

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Stereotactic body radiotherapy for pulmonary oligometastases from esophageal cancer: Results and prognostic factors

Abstract

Keywords

UN SDGs

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