Strategies for bioremediation of polychlorinated biphenyls

Yoshiyuki Ohtsubo, Toshiaki Kudo, Masataka Tsuda, Yuji Nagata

Research output: Contribution to journalShort surveypeer-review

88 Citations (Scopus)


Polychlorinated biphenyls (PCBs) are serious environmental pollutants that threaten both the natural ecosystem and human health. For remediation of environments contaminated with PCBs, several approaches that exploit the potential of microbes to degrade PCBs have been developed. These approaches include improvement of PCB solubilization and entry into the cell, pathway and enzyme engineering, and control of enzyme expression. In this mini-review, we briefly summarize these strategies and provide potentially useful knowledge for the further improvement of the bacterial breakdown of PCBs.

Original languageEnglish
Pages (from-to)250-258
Number of pages9
JournalApplied Microbiology and Biotechnology
Issue number3
Publication statusPublished - 2004 Aug


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