Abstract
Following the multiplication of biochemical, biophysical and structural studies describing cadherin molecules and their interactions, several ideas have emerged to explain the mechanisms of cadherin-mediated cell adhesion. Although different models were proposed for cadherin interactions, a consensus has come forth considering lateral dimerization of cadherins as being a central component of the cell-cell adhesion process. This review summarizes the recent development in structural studies of cadherins.
| Original language | English |
|---|---|
| Pages (from-to) | 359-367 |
| Number of pages | 9 |
| Journal | Cellular and Molecular Life Sciences |
| Volume | 55 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - 1999 |
Keywords
- Cadherin
- Calcium
- Cell adhesion
- Dimerization
- Protein interaction