Structure and expression of a novel rat RegIII gene

Suzuki Yoshihisa, Yonekura Hideto, Watanabe Takuo, Unno Michiaki, Moriizumi Shigeki, Miyashita Hikari, Okamoto Hiroshi

Research output: Contribution to journalArticlepeer-review

20 Citations (Scopus)

Abstract

We have isolated a rat cDNA and a novel gene, Reg (regeneration-promoting gene). The cDNA encodes a 174-aminoacid (aa) RegIII protein with a 25-aa signal peptide. The RegIII gene spans 2.7 kb and consists of six exons and five introns. RegIII was expressed in regenerating pancreatic islets, but not in normal islets.

Original languageEnglish
Pages (from-to)315-316
Number of pages2
JournalGene
Volume144
Issue number2
DOIs
Publication statusPublished - 1994 Jul 8

Keywords

  • Recombinant DNA
  • Reg/PSP gene family
  • growth factor
  • nucleotide sequence
  • pancreatic β-cells
  • regenerating islet cDNA library

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