Study of brain activation during the complicated hand motor task (Luria' s fist-edge-palm test) by functional MRI

A. Umetsu, S. Higano, S. Takahashi, T. Murata, J. Okuda, T. Tsukiura, T. Fujii, A. Yamadori, M. Sugiura, K. Inoue, R. Kawashima, H. Fukuda

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Abstract

The fist-edge-palm test (FEP) was introduced by Luria to detect dynamic apraxia. Luria believed its impairment was closely related to contralateral frontal lobe damage. However, this presumption still remains controversial. In this study, we applied this test to normal subjects and confirmed the activation in the whole brain. The subjects were instructed to perform the FEP, fist-palm, palm-edge, and fist-edge tasks with their right hand, and control state with no voluntary movement during the scan. The contralateral precentral, postcentral, premotor, supplementary motor, and parietal association areas and bilateral cerebellum were activated commonly in each task. The percentage of change in signal intensity was greater in the contralateral premotor and parietal association areas and bilateral cerebellum during the FEP than the other tasks. We suspected that these areas played an important role for executing the FEP with right hand.

Original languageEnglish
Pages (from-to)1515-1523
Number of pages9
JournalJapanese Journal of Clinical Radiology
Volume45
Issue number12
Publication statusPublished - 2000

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