Study of the binding mode of a chromophoric host zinc protoporphyrin with histamine

Ai Jun Tong; Chun Yuan Tong; Qing Yi Yang; Yuichi Kato; Seiichi Nishizawa; Norio Teramae

Study of the binding mode of a chromophoric host zinc protoporphyrin with histamine

Ai Jun Tong, Chun Yuan Tong, Qing Yi Yang, Yuichi Kato, Seiichi Nishizawa, Norio Teramae

SCI - Chemistry

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Abstract

Molecular recognition of histamine by Zn(II)-protoporphyrin (ZnPP) in water was investigated by using UV-Vis titration. An NOE mode of ¹H NMR was used to study the host-guest binding in DMSO-d₆ solution. Changes of proton chemical shifts for both ZnPP and histamine before and after complexing and a computer aided structure simulation confirmed our suggested binding mode that two hydrogen bonds between amino group of histamine and the two carboxylic acid groups of ZnPP as well as coordination of zinc to imidazole contribute to the binding.

Original language	English
Pages (from-to)	905-910
Number of pages	6
Journal	Acta Chimica Sinica
Volume	62
Issue number	9
Publication status	Published - 2004

Keywords

H NMR
Histamine
Molecular orbit model
UV-Vis
Zn(II)-protoporphyrin

Cite this

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title = "Study of the binding mode of a chromophoric host zinc protoporphyrin with histamine",

abstract = "Molecular recognition of histamine by Zn(II)-protoporphyrin (ZnPP) in water was investigated by using UV-Vis titration. An NOE mode of 1H NMR was used to study the host-guest binding in DMSO-d6 solution. Changes of proton chemical shifts for both ZnPP and histamine before and after complexing and a computer aided structure simulation confirmed our suggested binding mode that two hydrogen bonds between amino group of histamine and the two carboxylic acid groups of ZnPP as well as coordination of zinc to imidazole contribute to the binding.",

keywords = "H NMR, Histamine, Molecular orbit model, UV-Vis, Zn(II)-protoporphyrin",

author = "Tong, {Ai Jun} and Tong, {Chun Yuan} and Yang, {Qing Yi} and Yuichi Kato and Seiichi Nishizawa and Norio Teramae",

year = "2004",

language = "English",

volume = "62",

pages = "905--910",

journal = "Acta Chimica Sinica",

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T1 - Study of the binding mode of a chromophoric host zinc protoporphyrin with histamine

AU - Tong, Ai Jun

AU - Tong, Chun Yuan

AU - Yang, Qing Yi

AU - Kato, Yuichi

AU - Nishizawa, Seiichi

AU - Teramae, Norio

PY - 2004

Y1 - 2004

N2 - Molecular recognition of histamine by Zn(II)-protoporphyrin (ZnPP) in water was investigated by using UV-Vis titration. An NOE mode of 1H NMR was used to study the host-guest binding in DMSO-d6 solution. Changes of proton chemical shifts for both ZnPP and histamine before and after complexing and a computer aided structure simulation confirmed our suggested binding mode that two hydrogen bonds between amino group of histamine and the two carboxylic acid groups of ZnPP as well as coordination of zinc to imidazole contribute to the binding.

AB - Molecular recognition of histamine by Zn(II)-protoporphyrin (ZnPP) in water was investigated by using UV-Vis titration. An NOE mode of 1H NMR was used to study the host-guest binding in DMSO-d6 solution. Changes of proton chemical shifts for both ZnPP and histamine before and after complexing and a computer aided structure simulation confirmed our suggested binding mode that two hydrogen bonds between amino group of histamine and the two carboxylic acid groups of ZnPP as well as coordination of zinc to imidazole contribute to the binding.

KW - H NMR

KW - Histamine

KW - Molecular orbit model

KW - UV-Vis

KW - Zn(II)-protoporphyrin

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M3 - Article

AN - SCOPUS:33750510553

SN - 0567-7351

VL - 62

SP - 905

EP - 910

JO - Acta Chimica Sinica

JF - Acta Chimica Sinica

IS - 9

ER -

Study of the binding mode of a chromophoric host zinc protoporphyrin with histamine

Abstract

Keywords

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