Study on estimation of MMSE score by using the latency of P300 and alpha wave

Koki Miwa, Tomohiro Yoshikawa, Takashi Furuhashi, Minoru Hoshiyama, Taeko Makino, Madoka Yanagawa, Yusuke Suzuki, Hiroyuki Umegaki, Masafumi Kuzuya

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

2 Citations (Scopus)

Abstract

The number of elderly people with dementia increases year by year, and about 20% of people in Japan over 65 years old are estimated to be dementia patients in 2030. Because dementia is difficult to be treated after the symptoms advance, early detection of dementia is important. The peak latency of P300 is one of the EEG (Electroencephalogram) features. It has been reported that the peak latency of P300 is dependent on MMSE (Mini-Mental State Examination) score. If MMSE score can be estimated by measuring the latency of P300, it is expected to be used for the early detection of dementia. However, no regression equation between MMSE score and the latency of P300 had been identified yet. The authors measured the peak latency of P300 of dementia patients who were attending the Geriatrics of Nagoya University hospital and identified a multiple regression equation with MMSE score as the objective variable, and the latency of P300, age, years of education, alpha wave power as the explanatory variables. The 95% confidence interval of estimated MMSE score was ±3.09.

Original languageEnglish
Title of host publicationProceedings - 2018 Joint 10th International Conference on Soft Computing and Intelligent Systems and 19th International Symposium on Advanced Intelligent Systems, SCIS-ISIS 2018
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages195-199
Number of pages5
ISBN (Electronic)9781538626337
DOIs
Publication statusPublished - 2018 Jul 2
EventJoint 10th International Conference on Soft Computing and Intelligent Systems and 19th International Symposium on Advanced Intelligent Systems, SCIS-ISIS 2018 - Toyama, Japan
Duration: 2018 Dec 52018 Dec 8

Publication series

NameProceedings - 2018 Joint 10th International Conference on Soft Computing and Intelligent Systems and 19th International Symposium on Advanced Intelligent Systems, SCIS-ISIS 2018

Conference

ConferenceJoint 10th International Conference on Soft Computing and Intelligent Systems and 19th International Symposium on Advanced Intelligent Systems, SCIS-ISIS 2018
Country/TerritoryJapan
CityToyama
Period18/12/518/12/8

Keywords

  • Alpha wave
  • Dementia
  • Mini Mental State Examination (MMSE)
  • Multiple regression analysis
  • Oddball paradigm
  • P300

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