@article{8bb2784b810a4eb183d9690811a18efe,
title = "Substituent effect on the yield of unpaired electrons in DNA bases studied by electron paramagnetic resonance",
abstract = "The physicochemical processes underlying the radiation sensitization of DNA by the K-shell photoabsorption of nitrogen and oxygen atoms are unclear. Accordingly, we evaluated electron paramagnetic resonance spectra of thin films of pyrimidine bases. By altering the substituents of the pyrimidine ring, we found a substituent effect on the yield of unpaired electrons induced by photoabsorption. The yield of the unpaired electrons of the DNA-base containing amino groups increased by the donation of electrons, and the yield of halogenated DNA-bases decreased by the withdrawal of electrons. These different physicochemical processes might affect DNA bases, leading to differences in DNA modification.",
author = "Toshitaka Oka and Akinari Yokoya and Kentaro Fujii and Yasushi Kino and Tsutomu Sekine",
note = "Funding Information: The authors gratefully thank Dr. Y. Saitoh and Mr. Y. Fukuda at SPring-8 for their help operating the beamline and the end-station. Soft X-ray irradiation was conducted with the approval of JASRI (2010B3811, 2011A3815, 2011B3815, 2012B3812, 2013A3812, 2013B3812, 2014A3812, 2014B3812, 2015A3812, and 2015B3812). This study was partially supported by a Grant-in-Aid for Science Research B (21310041 and 15H02823) and a Grant-in-Aid for Challenging Exploratory Research (15K12211) from The Japan Society for the Promotion of Science (JSPS). Publisher Copyright: {\textcopyright} 2018 Author(s).",
year = "2018",
month = dec,
day = "10",
doi = "10.1063/1.5055722",
language = "English",
volume = "113",
journal = "Applied Physics Letters",
issn = "0003-6951",
publisher = "American Institute of Physics",
number = "24",
}