Successful treatment of adult-onset erythromelalgia with steroid pulse and pregabalin

Aya Kakizaki, Taku Fujimura, Yumi Kambayashi, Akiko Watabe, Setsuya Aiba

Research output: Contribution to journalArticlepeer-review

11 Citations (Scopus)


Adult-onset erythromelalgia (EM) is a rare disease characterized by episodic bouts of burning pain and erythema for which the optimal therapy is unclear. In this report, we describe a 68-year-old Japanese woman with adult-onset EM. Intravenous administration of methylprednisolone sodium succinate 1,000 mg/day dramatically improved her pain as evaluated by the visual analog scale. Although the patient's pain gradually developed again, it could be controlled with pregabalin. Our present case might suggest a possible, optimal therapy for adult-onset EM.

Original languageEnglish
Pages (from-to)242-246
Number of pages5
JournalCase Reports in Dermatology
Issue number3
Publication statusPublished - 2012 Apr 20


  • Erythromelalgia
  • Pregabalin
  • Steroid pulse


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