Sudden disappearance of the blood flow in a case of pancreatic acinar cell carcinoma

Atsushi Kanno, Atsushi Masamune, Shin Hamada, Kazuhiro Kikuta, Kiyoshi Kume, Morihisa Hirota, Kentaro Shima, Takaho Okada, Fuyuhiko Motoi, Fumiyoshi Fujishima, Kazuyuki Ishida, Michiaki Unno, Tooru Shimosegawa

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3 Citations (Scopus)


A 55-year-old man was referred to our hospital for a further examination of a pancreatic cystic tumor with a solid component exhibiting vascularity. A few days later, the patient was admitted with a complaint of sudden severe epigastric pain. Enhanced CT showed the loss of vascularity in the tumor. In particular, contrastenhanced endoscopic ultrasonography (EUS) clearly demonstrated the disappearance of the blood flow, and a histological examination revealed acinar cell carcinoma with central necrosis. To our knowledge, this is the first case in the literature of acinar cell carcinoma associated with the sudden disappearance of vascularity. In this case, contrast-enhanced harmonic EUS was especially useful for assessing the degree of vascularity.

Original languageEnglish
Pages (from-to)2589-2593
Number of pages5
JournalInternal Medicine
Issue number22
Publication statusPublished - 2014


  • Computed tomography
  • Contrast-enhanced harmonic EUS
  • Pancreatic tumor
  • Pancreatoduodenectomy


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