Sudden, unexpected infant death due to pulmonary arterial hypertension

Yui Igari, Tadashi Hosoya, Yoshie Hayashizaki, Tsukasa Ohuchi, Akihito Usui, Yusuke Kawasumi, Masaki Hashiyada, Masato Funayama

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)


A 3-year-old girl with no particular medical history complained of a stomachache and died on the way to the hospital. The autopsy revealed marked right ventricular hypertrophy and dilation with no other cardiac abnormalities. Microscopically, the pulmonary small arteries showed marked medial hypertrophy and varying degrees of intimal and adventitial thickening. We supposed that the cause of death was attributable to pulmonary arterial hypertension (PAH). PAH is a rare disease that can cause sudden, unexpected death at any age. Forensic pathologists should consider PAH in the differential diagnosis of sudden death.

Original languageEnglish
Pages (from-to)44-47
Number of pages4
JournalLegal Medicine
Issue number1
Publication statusPublished - 2014 Jan


  • Pulmonary arterial hypertension (PAH)
  • Right ventricular hypertrophy
  • Sudden death in infancy


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