Sugar-induced disintegration of layer-by-layer assemblies composed of concanavalin A and glycogen

Katsuhiko Sato; Yoko Imoto; Jun Sugama; Shunsuke Seki; Hiroyuki Inoue; Tsuyoshi Odagiri; Tomonori Hoshi; Jun Ichi Anzai

doi:10.1021/la048059x

Sugar-induced disintegration of layer-by-layer assemblies composed of concanavalin A and glycogen

Katsuhiko Sato, Yoko Imoto, Jun Sugama, Shunsuke Seki, Hiroyuki Inoue, Tsuyoshi Odagiri, Tomonori Hoshi, Jun Ichi Anzai

HOSP - Clinical Research, Innovation and Education Center

Tohoku University

Research output: Contribution to journal › Article › peer-review

131 Citations (Scopus)

Abstract

The glucose-sensitive multilayer films composed of concanavalin A (Con A)-dextran were studied for developing optical glucose sensors. The multilayer films were prepared on the surface of a quartz slide, which was treated in diclorodimethylsilane overnoght at room temperature. It was reported that the Con A-glycogen multilayer films were sensitive to sugars and can be fully disintegrated in the presence of D-glucose, D-mannose, and derivatives. The sugar-induced disintegration of Con A-glycogen films was evaluated by measuring absorption spectra of the films. The stability of the Con A-glycogen multilayer films, in the sugar-free buffer solutions at pH 6, 7, and 8, was also studied.

Original language	English
Pages (from-to)	797-799
Number of pages	3
Journal	Langmuir
Volume	21
Issue number	2
DOIs	https://doi.org/10.1021/la048059x
Publication status	Published - 2005 Jan 18

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abstract = "The glucose-sensitive multilayer films composed of concanavalin A (Con A)-dextran were studied for developing optical glucose sensors. The multilayer films were prepared on the surface of a quartz slide, which was treated in diclorodimethylsilane overnoght at room temperature. It was reported that the Con A-glycogen multilayer films were sensitive to sugars and can be fully disintegrated in the presence of D-glucose, D-mannose, and derivatives. The sugar-induced disintegration of Con A-glycogen films was evaluated by measuring absorption spectra of the films. The stability of the Con A-glycogen multilayer films, in the sugar-free buffer solutions at pH 6, 7, and 8, was also studied.",

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T1 - Sugar-induced disintegration of layer-by-layer assemblies composed of concanavalin A and glycogen

AU - Sato, Katsuhiko

AU - Imoto, Yoko

AU - Sugama, Jun

AU - Seki, Shunsuke

AU - Inoue, Hiroyuki

AU - Odagiri, Tsuyoshi

AU - Hoshi, Tomonori

AU - Anzai, Jun Ichi

PY - 2005/1/18

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N2 - The glucose-sensitive multilayer films composed of concanavalin A (Con A)-dextran were studied for developing optical glucose sensors. The multilayer films were prepared on the surface of a quartz slide, which was treated in diclorodimethylsilane overnoght at room temperature. It was reported that the Con A-glycogen multilayer films were sensitive to sugars and can be fully disintegrated in the presence of D-glucose, D-mannose, and derivatives. The sugar-induced disintegration of Con A-glycogen films was evaluated by measuring absorption spectra of the films. The stability of the Con A-glycogen multilayer films, in the sugar-free buffer solutions at pH 6, 7, and 8, was also studied.

AB - The glucose-sensitive multilayer films composed of concanavalin A (Con A)-dextran were studied for developing optical glucose sensors. The multilayer films were prepared on the surface of a quartz slide, which was treated in diclorodimethylsilane overnoght at room temperature. It was reported that the Con A-glycogen multilayer films were sensitive to sugars and can be fully disintegrated in the presence of D-glucose, D-mannose, and derivatives. The sugar-induced disintegration of Con A-glycogen films was evaluated by measuring absorption spectra of the films. The stability of the Con A-glycogen multilayer films, in the sugar-free buffer solutions at pH 6, 7, and 8, was also studied.

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Sugar-induced disintegration of layer-by-layer assemblies composed of concanavalin A and glycogen

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